A comparison of high viscosity bone cement and low viscosity bone cement vertebroplasty for severe osteoporotic vertebral compression fractures

Zhang, Liang; Wang, Jingcheng; Feng, Xinmin; Tao, Yajun; Yang, Jiandong; Wang, Yongxiang; Zhang, Shengfei; Cai, Jiyang; Huang, Jingsong

doi:10.1016/j.clineuro.2014.11.018

Cited by 49 publications

(65 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, when puncturing bilaterally, the angle of puncture needle can be adjusted so that the two puncture needles point to the upper or lower endplate respectively [34], using high-viscosity cement [35], using hydraulic assistant device to inject bone cement slowly and uniformly may be more bene cial for a better distribution of bone cement [36]. High-viscosity cement has the advantages of fast bonding with bone, long working time window and low polymerization temperature [37]. A meta-analysis found that high-viscosity cement has signi cant advantages in pain improvement, recovery of cobb angle and cement leakage comparing with low-viscosity cement [38].…”

Section: Discussionmentioning

confidence: 99%

The Effect of Bone Cement Distribution on the Outcome of Percutaneous Vertebroplasty: A Case cohort study

Tan

Wen²,

Guo

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: To analyze the effect of different types of bone cement distribution after percutaneous vertebroplasty (PVP) in patients with osteoporotic vertebral compression fracture (OVCF). Methods: 137 patients with single level OVCF who underwent PVP were retrospectively analyzed. The patients were divided into two groups according to bone cement distribution. Group A: bone cement contacted both upper and lower endplates; Group B: bone cement missed at least one endplate. Group B was divided into 3 subgroups. Group B1: bone cement only contacted the upper endplates; Group B2: bone cement only contacted the lower endplates; Group B3: bone cement only located in the middle of vertebral body. The visual analogue scale (VAS) score at 24 hours post operation and last follow-up, anterior vertebral height restoration ratio (AVHRR), anterior vertebral height loss ratio (AVHLR), local kyphotic angle change and vertebral body recompression rate were compared. Results: 24 hours post operation, the pain of all groups were significantly improved. The average follow-up time was 15.3 ± 6.3 (6-24) months. At last follow-up, the VAS score of group A was lower than that of group B. There were 14 cases (10.2%) of adjacent vertebral fracture, 5 cases (8.6%) in group A and 9 cases (11.4%) in group B. There were 9 cases (6.6%) of cement leakage, 4 cases (6.9%) in group A and 5 cases (6.3%) in group B. At last follow-up, there were 16 cases (11.7%) of vertebral body recompression, including 3 cases (5.2%) in group A and 13 cases (16.5%) in group B. There was no significant difference in AVHRR between two groups. Local kyphotic angle change was significant larger in group B. At last follow-up, AVHLR in group B was higher than that in group A. In subgroup analysis, there was no significant difference in VAS score, local kyphotic angle change, vertebral recompression rate, AVHRR or AVHLR. Conclusions: If the bone cement fully contacted both the upper and lower endplates, it can better restore the strength of the vertebral body and maintain the height of the vertebral body, reduce the risk of the vertebral body recompression and long-term pain.

show abstract

Section: Discussionmentioning

confidence: 99%

The Effect of Bone Cement Distribution on the Outcome of Percutaneous Vertebroplasty: A Case cohort study

Tan

Wen²,

Guo

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…PVP treatment can improve the thermochemical damage to nerve terminals after OVF and the mechanical stability of the whole vertebrae is enhanced after the application of bone cement. Previous studies [14] have pointed out that the efficacy of low-viscosity bone cement and high-viscosity bone cement is comparable in the treatment of OVF. Whereas, the incidence of venous leakage and paravertebral leakage with low-viscosity bone cement is high as well as fatal [15] .…”

mentioning

confidence: 94%

Comparative Efficacy and Safety of High-viscosity versus Low-viscosity Bone Cement in the Treatment of Osteoporotic Vertebral Fractures

Yu¹,

Sendong²

2020

pharmaceutical-sciences

View full text Add to dashboard Cite

Yu et al.: Efficacy and Safety Comparison of Low-viscosity Bone Cement This study was to compare the clinical effects of high-viscosity with low-viscosity bone cement in percutaneous vertebroplasty for the treatment of osteoporotic vertebral fracture. A total of 112 patients with osteoporotic vertebral fracture received percutaneous vertebroplasty treatment from March 2015 to March 2017 in the Zhongda Hospital Southeast University were enrolled and divided into the high-viscosity group (n=56) and low-viscosity group (n=56) according to the cement used. Visual analogue scale, Oswestry disability index, Cobb angle and leakage were observed before operation, 2 days after operation and 4 months after operation. There was no significant difference in visual analogue scale score, Oswestry disability index score or Cobb angle between the 2 groups before operation. However, the visual analogue scale score, Oswestry disability index score and Cobb angle of the high-viscosity group were lower than those of the low-viscosity group 2 d after operation and 4 months after operation. Besides, the proportion of leakage into the venous area, intervertebral area, paravertebral area and the total leakage rates in the high-viscosity group were lower than those in the low-viscosity group. In conclusion, compared to the low-viscosity bone cement, the high-viscosity bone cement could significantly relieve the postoperative pain, restore the height of vertebrae and reduce the venous, intervertebral and paravertebral leakage rate. Therefore, high-viscosity bone cement can be used as the first choice for the treatment of osteoporotic vertebral fracture.

show abstract

“…High-viscosity bone cement was applied to reduce the leakage risk [11][12][13][14] , with the advantage of optionally long injection time, allowing surgeons to determine whether the injection would be continued before cement leakage takes place, thus prominently improving operative safety [15] .…”

mentioning

confidence: 99%

High-viscosity bone cement for vertebral compression fractures: a prospective study on intravertebral diffusion of bone cement

wang

Jin

2020

Preprint

View full text Add to dashboard Cite

Objective Bone cement leakage causes severe complication following percutaneous vertebroplasty. This study probed the diffusion and leakage status of bone cement injected within diverged time duration, so as to find the optimal injection time for bone cement. Methods A total of 70 patients with osteoporotic vertebral compression fractures with a symptom of low back pain, who underwent treatment at hospital were enrolled in this study. Patients were randomized into three groups: <180 s, 180-300, and >300 s of injection time duration from the beginning to the completion of the injection. The scenarios of vertebral bone cement leakage and diffusion were inspected using postoperative CT. Results The diffusion coefficient was higher in group A than in group B whereas it was higher in group B than in group C, but without statistical significance among the three groups. The leakage rate was without statistical significance among the three groups. The injection time of bone cement was negatively correlated with the diffusion coefficient, at the correlation coefficient of -0.253. Conclusions The diffusion coefficient of high-viscosity bone cement is likely negatively correlated with the injection time, and the leakage rate of high-viscosity bone cement probably does not reduce with the prolongation of injection time.

show abstract

A comparison of high viscosity bone cement and low viscosity bone cement vertebroplasty for severe osteoporotic vertebral compression fractures

Cited by 49 publications

References 33 publications

The Effect of Bone Cement Distribution on the Outcome of Percutaneous Vertebroplasty: A Case cohort study

The Effect of Bone Cement Distribution on the Outcome of Percutaneous Vertebroplasty: A Case cohort study

Comparative Efficacy and Safety of High-viscosity versus Low-viscosity Bone Cement in the Treatment of Osteoporotic Vertebral Fractures

High-viscosity bone cement for vertebral compression fractures: a prospective study on intravertebral diffusion of bone cement

Contact Info

Product

Resources

About