“…Under these circumstances, a small lesion can be easily missed by biopsy, but the Papanicolaou smear obtains a sample of cells representing the entire desquamating area of the cervix. False negative results are rare; Graham and associates (2) state that they are relatively evenly distributed among the various stages of the disease, whereas false negative biopsy findings are more frequent in the early stages. Smears reported as “unsatisfactory” should be repeated.…”