A Comprehensive and Critical Review on Ethnopharmacological Importance of Desert Truffles: <i>Terfezia claveryi, Terfezia boudieri</i>, and <i>Tirmania nivea</i>

Veeraraghavan, Vishnu Priya; Hussain, Sardar; Balakrishna, Janardhana Papayya; Dhawale, Lavina; Kullappan, Malathi; Ambrose, Jenifer Mallavarapu; Mohan, Surapaneni Krishna

doi:10.1080/87559129.2021.1889581

Cited by 20 publications

(16 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The silylated metabolites of the hydromethanolic extracts of TN and TP were analyzed using GC–MS. Silylation process, instrument specifications, and identification of the chemical constituents of the essential oil are described in Supporting Information S1 (Darwish et al, 2021; El‐Garawani et al, 2020; Khaled et al, 2021; Veeraraghavan et al, 2021).…”

Section: Methodsmentioning

confidence: 99%

“…It is well known that mushrooms have medicinal and nutritional value. Due to their ethnomycological importance, ectomycorrhizal wild mushrooms of the orders Tuberales and Pezizales with hypogeous fruiting bodies are receiving more attention (Bradai et al, 2015; Thomas et al, 2019; Veeraraghavan et al, 2021). Various names for truffles, commonly referred to as desert truffles, include Kam'aah, Gibbah, Eblaj, Fug'a, Nabat Al Radh, Khlaasi, Zubaidi, Terfas, Nahbaat alra'ad, Faga Al Toyoor, Asqal, N'abbas, Banat Ober, and Bidat El Ardh (Thomas et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

HPLC and GC–MS–based metabolic profiles and in vivo anticonvulsant, sedative, and antinociceptive potentials of truffles Tirmania nivea and Tirmania pinoyi hydromethanolic extracts in mice

Aboutabl

Elkhateeb

Masoud

et al. 2022

Biomedical Chromatography

View full text Add to dashboard Cite

GC-MS and HPLC analyses of the hydromethanolic extracts of the truffles Tirmania nivea (TN) and Tirmania pinoyi (TP) revealed the presence of 18 metabolites and 11 polyphenols, respectively. In vivo, TP extract protected against subcutaneous pentylenetetrazole (scPTZ) and maximal electric shock (MES)-induced convulsions faster than TN extract. TP extract (100 and 300 mg/kg) showed 100% protection and longer duration than TN extract in the scPTZ test. Similarly, at 300 mg/kg, TP demonstrated a quicker start (75%) and longer duration of action (100%) than TN in MES test. In the scPTZ test, ED 50 of TP demonstrated greater anticonvulsant efficacy than that of TN. In mice given TP and TN treatments, the brain GABA levels noticeably increased. TP (100 and 300 mg/kg) produced a notable sedative effect in open-field test, whereas TN (100 or 300 mg/kg) and TP (300 mg/kg) reduced sleep latency by 52%, 45%, and 79%, respectively. In writhing test, TN (100 or 300 mg/kg) significantly enhanced analgesic efficacy by 50 and 87%, respectively.Comparatively, in formalin test, TP and TN at a dosage of 300 mg/kg decreased the length of the licking by 34 and 59%, respectively. For the first time, this study explains the anticonvulsant, sedative, central, and peripheral analgesic activities of truffle extracts.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

HPLC and GC–MS–based metabolic profiles and in vivo anticonvulsant, sedative, and antinociceptive potentials of truffles Tirmania nivea and Tirmania pinoyi hydromethanolic extracts in mice

Aboutabl

Elkhateeb

Masoud

et al. 2022

Biomedical Chromatography

View full text Add to dashboard Cite

show abstract

“…Truffles are well known for their unique flavor and nutritional value in addition to that few bio-activity parameters are also reported in truffles such as antioxidant activity, antimicrobial activity, antiviral activity, antimutagenic activity, anti-inflammatory activity, and hepatoprotective activity etc. [20][21][22][23][24][25][26] . Stanikunaite et al, carried out a study in which twentytwo species of hypogeous truffles and other fungi similar to truffles are screened for bioactivities 24 .…”

Section: Biochemical Properties Of Trufflesmentioning

confidence: 99%

Biochemical and Health Properties of Truffles

et al. 2021

View full text Add to dashboard Cite

Truffles are the most expensive edible mushrooms refer to genus tuber which grows symbiotically in plant roots such as oaks and hazels. Truffles are underground mushrooms also known for their characteristic earthy flavor which is the major reason for their special place in the culinary. Their characteristic intense aroma helps them in reproduction by attracting small animals. Truffles can survive in a wide range of environments such as deep forests as well as deserts. The most expensive varieties of truffles include Tuber melanosporum (Black truffle), Tuber magnatum (White truffle), Tuber aestivum (Burgundy truffle), Tirmania nivea, and Terfezia chlaveryi (Dessert truffles). Truffles vary in their composition and flavor profile from species to species. The major volatile components which are responsible for truffle aroma are aldehydes, ketones, sulfur compounds, alcohols, and esters. Truffles are highly nutritious, rich in antioxidants, and have therapeutic properties such as antimicrobial activity, antiviral activity, antimutagenic activity, anti-inflammatory activity, hepatoprotective activity, etc. The major active components present in truffle are tuberoside, phenolics, anandamide, and ergosterol.

show abstract

“…Terfezia claveryi is a source of carbohydrates, amino acids (methionine, cysteine, tryptophan and lysine), proteins, fats, fibers, minerals and ascorbic acids [ 8 , 12 ]. In addition, it contains phenolic compounds and tocopherols in minor amounts [ 10 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

“…It is also used to treat skin diseases, wounds and as an aphrodisiac [ 7 ]. Several biological activities have been explored for Terfezia claveryi, including antibacterial, antioxidant, potential hepatoprotective, antimutagenic, anti-inflammatory and anticancer activities [ 12 ]. The antioxidant property of truffles has elevated the question of whether they can be used as a functional/medical food that could play a role in health maintenance and disease prevention, including diabetes [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

In Vitro and In Vivo Antidiabetic Activity, Phenolic Content and Microscopical Characterization of Terfezia claveryi

et al. 2022

View full text Add to dashboard Cite

Terfezia claveryi (T. claveryi) is used by traditional healers in the Middle East region to treat several diseases, including diabetes. The present study evaluated the total phenolic and investigated the blood-glucose-lowering potential of different aqueous extracts of this selected truffle using in vitro and in vivo models. The phytochemical profile was examined using UPLC-MS. The macerate and the microwave-assisted extract were the richest in phenolic compounds. All T. claveryi extracts exhibited a remarkable α-glucosidase inhibitory effect in vitro, with an IC50 of 2.43, 3.26, 5.18 and 3.31 mg/mL for the aqueous microwave-assisted extract macerate, infusion and decoction, respectively. On the other hand, in the high-fat diet alloxan-induced diabetic mice model, all tested crude aqueous extracts exhibited a significant antihyperglycemic activity (p < 0.05). Four hours after the administration of the 250 mg/kg dose, the macerate was able to induce a 29.4% blood-glucose-lowering effect compared to a 24.8% reduction induced by the infusion, which was sustained for a further two hours. The hypoglycemic effect (29.3% and 32.4%) was also recorded six hours after the administration of the single dose 500 mg/kg of the macerate and the infusion, respectively. Truffle extracts exhibited antidiabetic activity both in vitro and in vivo, providing a rationale for the traditional use as a natural hypoglycemic.

show abstract

A Comprehensive and Critical Review on Ethnopharmacological Importance of Desert Truffles: Terfezia claveryi, Terfezia boudieri, and Tirmania nivea

Cited by 20 publications

References 55 publications

HPLC and GC–MS–based metabolic profiles and in vivo anticonvulsant, sedative, and antinociceptive potentials of truffles Tirmania nivea and Tirmania pinoyi hydromethanolic extracts in mice

HPLC and GC–MS–based metabolic profiles and in vivo anticonvulsant, sedative, and antinociceptive potentials of truffles Tirmania nivea and Tirmania pinoyi hydromethanolic extracts in mice

Biochemical and Health Properties of Truffles

In Vitro and In Vivo Antidiabetic Activity, Phenolic Content and Microscopical Characterization of Terfezia claveryi

Contact Info

Product

Resources

About