2023
DOI: 10.1021/acs.jchemed.3c00134
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A Comprehensive Inquiry-Based Comparative Experiment for an Undergraduate Organic Chemistry Laboratory Course: Elucidating the Formation Process of N-Phenylbenzamide

Xinyun Zhao,
Tsunghsueh Wu,
Xi Chen
et al.

Abstract: An inquiry-based learning approach was implemented into comprehensive organic chemistry experiments focusing on the formation process of N-phenylbenzamide from the reaction between N-benzylideneaniline and benzoyl peroxide in commercial dimethyl sulfoxide. Students conducted comparative experiments using alternative reagents or reaction conditions to produce products. After structure determination of the products by NMR and GC–MS, the observed structural difference can lead to the conclusion that the CN doubl… Show more

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