A Comprehensive Study of Extraction of L-Lysine withSec-Octylphenoxy Acetic Acid in Sulfonated Kerosene

Abstract

Extraction of L-lysine with sec-octylphenoxy acetic acid (CA-12) in sulfonated kerosene was investigated under different pH and CA-12 concentrations, and optimized conditions were determined. Half-saturation fluorometric analysis and atomic force microscopy showed that the electrovalent bond between L-lysine and CA-12 acted as the main force to partition L-lysine into organic phase. Moreover, the mathematically analyzed extraction process indicated that the extractive complex was a 1:2 L-lysine • CA-12 structure. The initial extraction efficiency could reach 78.9 ± 1.2% and the total strip extraction efficiency after three strip extractions could reach 95.7 ± 1.8% by using a dilute KCl solution.

Mechanisms of L‐lysine extraction with sec‐octylphenoxy acetic acid in sulfonated kerosene

“…Liquid–liquid extraction (LLE) is a process of transferring a chemical compound from one liquid phase to the other liquid phase . In recent decades, LLE has been becoming more attractive for separation and purification of amino acids due to the high extraction efficiency, saving in solvent and energy, possibility of room temperature operation, continuous production and low cost . Amino acids dissociate in aqueous solutions, forming characteristic ionic species (i.e.…”

“…The essential amino acid L‐Lys is an important amino acid applied as a special chemical in medicaments, chemical agents, food materials and feed additives . The separation and purification of L‐Lys using an LLE method is prospective . Several authors have studied the separation and purification of L‐Lys.…”

“…Sulfonated kerosene, also known as solvent naphtha #260, was used as diluent, with the advantages of less aromatics, low toxicity, high safety, no odor, pure quality, low sulfur, environmental protection and strong solubility . Sulfonated kerosene was immiscible with L‐Lys aqueous solution, and it showed high selectivity and stability in L‐Lys extraction . Therefore, sulfonated kerosene was selected to be the diluent for extractant CA‐12 in L‐Lys extraction.…”

“…32 -34 The separation and purification of L-Lys using an LLE method is prospective. 7,35,36 Several authors have studied the separation and purification of L-Lys. Wu et al studied the separation of low concentration L-Lys from aqueous solution by solvent sublation with dodecylbenzenesulforic acid (DBSA) as the surfactant and D2EHPA as the extractant.…”

“…48 Sulfonated kerosene was immiscible with L-Lys aqueous solution, and it showed high selectivity and stability in L-Lys extraction. 7 Therefore, sulfonated kerosene was selected to be the diluent for extractant CA-12 in L-Lys extraction.…”