A comprehensive study on Industry 4.0 in the pharmaceutical industry for sustainable development

Sharma, Dinesh K.; Patel, Paresh K.; Shah, Manan

doi:10.1007/s11356-023-26856-y

Cited by 28 publications

(11 citation statements)

References 36 publications

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“…Pharmaceutical companies employ quality management systems and implement continuous improvement methodologies to drive sustainable practices. This includes setting targets, measuring performance, and implementing corrective actions to enhance sustainability performance and reduce environmental impact [68,69]. By adopting sustainable manufacturing practices, the pharmaceutical industry can contribute to a more environmentally friendly and socially responsible approach to drug production.…”

Section: Overview Of Sustainable Manufacturing Practicesmentioning

confidence: 99%

Seaweed: a sustainable solution for greening drug manufacturing in the pursuit of sustainable healthcare

Pereira,

Cotas

2024

Explor Drug Sci

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The environmental impact of drug manufacturing raises concerns about sustainability in healthcare. To address this, exploring alternative approaches to drug production is crucial. This review focuses on seaweed as a sustainable resource for greening drug manufacturing processes. Seaweed offers advantages such as renewability, abundance, and a positive environmental footprint. The review begins by providing an overview of sustainable drug manufacturing practices and the challenges faced in achieving sustainability. It then discusses seaweed as a sustainable resource, including cultivation techniques and environmental benefits. Seaweed has various applications in drug manufacturing, including extracting and purifying bioactive compounds with potential therapeutic properties. Seaweed’s role in developing green technologies, such as seaweed-based excipients, biodegradable packaging materials, and as a source of sustainable energy for drug manufacturing processes, is highlighted. The environmental and economic implications of incorporating seaweed-based solutions are discussed, emphasizing reduced carbon footprint and cost-effectiveness. Regulatory and industrial perspectives are addressed, examining challenges, and opportunities for implementing seaweed-based drug manufacturing. Collaboration between academia, industry, and regulatory bodies is crucial for successful integration. The review presents future directions and opportunities, including emerging trends and innovations in seaweed-based drug manufacturing, areas for further research, policy development, and industry engagement recommendations. Incorporating seaweed into drug production facilitates a reduction in environmental impact, promotes resource efficiency, and contributes to sustainable healthcare. This review showcases seaweed-based solutions as a means to foster a greener future for drug manufacturing, addressing environmental concerns, and promoting sustainability.

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Section: Overview Of Sustainable Manufacturing Practicesmentioning

confidence: 99%

Seaweed: a sustainable solution for greening drug manufacturing in the pursuit of sustainable healthcare

Pereira,

Cotas

2024

Explor Drug Sci

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“…Studies pertaining to technologies like blockchain, AI and circular supply chains, etc. have also used MCDM methodologies (Bonab et al, 2023;Asadi et al, 2023;Bai et al, 2022;Khan and Ali, 2022;La Torre et al, 2023) Additionally, this approach fosters the development of innovative and eco-friendly pharmaceutical products, thereby promoting a greener and more sustainable future for the industry (Sharma et al, 2023). TA studies have been extensively done in past literature but the quantitative selection of a TA theory that can be put to use is not seen very often.…”

Section: Mcdm Modelsmentioning

confidence: 99%

“…The implementation of Sustainable Pharma 4.0 not only enhances productivity but also addresses ecological concerns, contributing to a more environmentally responsible pharmaceutical industry that aligns with global sustainability objectives. Additionally, this approach fosters the development of innovative and eco-friendly pharmaceutical products, thereby promoting a greener and more sustainable future for the industry (Sharma et al. , 2023).…”

Section: Literature Reviewmentioning

confidence: 99%

Technology adoption theories towards environmentally sustainable pharma 4.0: a rational selection approach

Toshniwal,

Jain,

Soni

et al. 2023

MEQ

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PurposeThis study is centered on the identification of the most appropriate Technology Adoption (TA) model for investigating the adoption of Industry 4.0 technologies within pharmaceutical and related enterprises. The aim is to facilitate a smooth transition to advanced technologies while concurrently achieving environmental sustainability.Design/methodology/approachSelection of a suitable TA theory is carried out using a hybrid multi-criteria decision-making (MCDM) approach incorporating PIvot Pairwise RElative Criteria Importance Assessment (PIPRECIA) and Fuzzy Measurement of alternatives and ranking according to Compromise solution (F-MARCOS) methods. A group of three experts is formulated for the ranking of criteria and alternatives based on those criteria.FindingsThe results indicate that out of all six TA models considered unified theory of acceptance and use of technology (UTAUT) model gets the highest utility function value, followed by the technical adoption model (TAM). Further, sensitivity analysis is conducted to confirm the validity of the MCDM model employed.Research limitations/implicationsChallenging times like COVID-19 pointed out the importance of technology in the pharmaceutical and healthcare sectors. TA studies in this area can help in the identification of critical factors that can assist pharmaceutical firms in their efforts to embrace emerging technologies, enhance their outputs and increase their efficiency.Originality/valueThe novelty of this research lies in the fact that the utilization of a TA theory prior to its implementation has not been witnessed in existing scholarly literature. The utilization of a TA theory, specifically within the pharmaceutical industry, can assist enterprises in directing their attention toward pertinent factors when contemplating the implementation of emerging technologies and achieving sustainable development.

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“…Pharmaceutical industries play a crucial role in the health of global population, offering therapeutic agents for both treating and preventing diseases, as well as by enhancing patients' quality of life by relieving them of pain and other symptoms. 1 From controlling hypertension 2 to the fast development of vaccine against SARS-CoV-2, 3 from HIV 4 to cancer, 5 active pharmaceutical ingredients (APIs) are critical for the development, well-being and longevity of populations all around the world. Despite their undeniable need in modern society, these active pharmaceutical ingredients present also a threat to ecosystems and public health due to their typical low absorption rate.…”

Section: Introductionmentioning

confidence: 99%

Fatty Acids-Based Eutectic Solvents Liquid Membranes for Removal of Sodium Diclofenac from Water

Afonso,

Caetano,

Florindo

et al. 2024

ACS Sustainable Resour. Manage.

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Nowadays, the scarcity of clean fresh water is a major concern to public health. One of the main issues linked with this topic is the unavoidable contamination of water bodies with active pharmaceutical ingredients, which results from production and metabolization of prescribed and over the counter drugs closely related to human health and wellbeing. As the currently available techniques for removal of micropollutants (MPs) from wastewater are not sufficiently broad, efficient, and cost effective, new sustainable alternatives are required to prevent the contamination of water bodies which can compromise the viability of aquatic ecosystems and, ultimately, life on earth as we know it. Herein, a natural eutectic solvent (ES), based on fatty acids, is proposed to remove important MPs, sodium diclofenac, the most used nonsteroid anti-inflammatory drug, and a plasticizer, Bisphenol A (BPA), through liquid−liquid extraction (LLE), as well as preparation of liquid membranes. The extraction of sodium diclofenac through LLE reached an efficiency of (97 ± 1)% that was maintained when shifting to the liquid membranes while reducing the quantity of solvent to only 1.5% of that required in LLE. These membranes were reused through 10 cycles of extraction without major loss of efficiency. The optimal extraction efficiency of BPA using ES supported in membranes reached (63 ± 1)%. The easy preparation of hydrophobic natural eutectic solvents-based absorbent materials through their impregnation in porous inert supports enables the development of highly efficient and costeffective adsorption technology for the removal MPs from water.

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A comprehensive study on Industry 4.0 in the pharmaceutical industry for sustainable development

Cited by 28 publications

References 36 publications

Seaweed: a sustainable solution for greening drug manufacturing in the pursuit of sustainable healthcare

Seaweed: a sustainable solution for greening drug manufacturing in the pursuit of sustainable healthcare

Technology adoption theories towards environmentally sustainable pharma 4.0: a rational selection approach

Fatty Acids-Based Eutectic Solvents Liquid Membranes for Removal of Sodium Diclofenac from Water

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