2012
DOI: 10.1002/cjoc.201201069
|View full text |Cite
|
Sign up to set email alerts
|

A Concise Total Synthesis of Amphidinin B

Abstract: A concise total synthesis of amphidinin B, a cytotoxic linear dicarboxylic acid associated with amphidinolide T marine macrolides, has been accomplished from the 19-membered cycloalkene intermediates designed for diverted total synthesis of amphidinolide T1 and T3-T5. The 1 H and 13 C NMR spectra of the synthesized amphidinin B in C 6 D 6 and CDCl 3 were compared with those for the natural and synthetic forms reported in the literature, showing solvent-dependence of the 1 H and 13 C NMR signals of amphidinin B… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
3
0

Year Published

2013
2013
2023
2023

Publication Types

Select...
5
1

Relationship

1
5

Authors

Journals

citations
Cited by 6 publications
(3 citation statements)
references
References 28 publications
0
3
0
Order By: Relevance
“…Three-dimensional (3D) carbon nanotube (CNT)-based macrostructures have recently received extensive attention because the outstanding properties of one- and two-dimensional nanostructures, such as nanotubes and graphene, have not been successfully translated into key engineering applications. However, experimental realization of a controlled macroscale 3D CNT architecture represents a huge challenge …”
mentioning
confidence: 99%
“…Three-dimensional (3D) carbon nanotube (CNT)-based macrostructures have recently received extensive attention because the outstanding properties of one- and two-dimensional nanostructures, such as nanotubes and graphene, have not been successfully translated into key engineering applications. However, experimental realization of a controlled macroscale 3D CNT architecture represents a huge challenge …”
mentioning
confidence: 99%
“…We included 38 trials from the database search and 9 unpublished studies from trial registries or other methods. Ultimately, 47 RCTs (comprising 7,798 patients) (10–56) performed between 1993 and 2021 were included. Twenty-one types of vasoactive agents were compared in the included trials, including single administration of NE, EP, enoximone (EX), dopexamine (DX), dobutamine (DB), dopamine (DA), levosimendan (LE), vasopressin (VP), TP, SP, phenylephrine (PE), placebo (PA) and other catecholamines (CE), as well as combined therapies including NE plus DB (NE_DB), NE plus DX (NE_DX), NE plus EP (NE_EP), NE plus TP (NE_TP), NE plus VP (NE_VP), TP plus DB (TE_DB), and TP plus CE (TP_CE).…”
Section: Resultsmentioning
confidence: 99%
“…In 1864 Schiff Hugo firstly reported the condensation reaction of the Primary Amine with active carbonyl compounds such as aldehydes, ketones, which generated a class of compounds with imino (Azomthine group) (-RC= N-), it was called the Schiff base. Synthesis of Schiff base is relatively easy [1][2] by flexible choicing different amine and aldehydes and ketones [3][4] . The structure of the ligand and metal complexes can open up from chain to cyclization , from single to multi-tooth gear.…”
Section: Introductionmentioning
confidence: 99%