A convenient and biogenetic type synthesis of few naturally occurring chromeno dihydrochalcones and their in vitro antileishmanial activity

Synthesis, characterization and in vitro biological evaluation of some new 1,3,5-triazine-chalcone hybrid molecules as Mycobacterium tuberculosis H37Rv inhibitors

“…Similarly, chalcones (α,β-unsatured ketones) captivated significant attention in drug discovery chemistry. Chalcones (α,β-unsatured ketones) have gained huge significance as these compounds exhibit several biological activities, such as antimicrobial [68], antiviral [69], antioxidant [70], radical inhibitor [71], antitumor [72], carbonic anhydrase inhibitor [73], xanthine oxidase inhibitor [74], antibacterial [75], plant growth regulator [76], free radical scavenger [77], anti-inflammatory [78] and analgesic [79].…”

Crystal structure of 3-amino-8-methoxy-1-phenyl-1H-benzo[f]chromene-2-carbonitrile, C21H16N2O2

“…In recent years, they have attracted considerable attention due to their antimicrobial [2,3], antileishmanial [4][5][6][7][8][9], anticancer [10][11][12][13][14][15], antiproliferative [22], antioxidant [16][17][18], hypertensive [14], antitumor [19][20][21] effects and activities, as well as proving potentially useful in the treatment of Alzheimer's disease [23] and schizophrenia disorder [24].…”

One pot synthesis of substituted 1H-benzo[f]chromen-3-yl-2H-chromen-2-one derivatives

“…Chromene derivatives are known to exhibit a wide range of biological activities, such as antifungal, antibacterial [1][2][3][4][5], antioxidative [6], antileishmanial [7], antitumor [8,9], hypotensive [9], antiproliferation [10,11], local anesthetic [12], antiallergenic [13,14], central nervous system activities and effects [15], as well as efficacious in the treatment of Alzheimer's disease [16] and schizophrenia disorder [17]. Coumarins are of scientific interest as anti-HIV agents [18], antituberculosis agents [19], cholinesterase and monoamine oxidase inhibitors [20], antioxidants and anti-inflammatory [21,22].…”