2024
DOI: 10.3390/bios14050247
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A Copper-Selective Sensor and Its Inhibition of Copper-Amyloid Beta Aggregation

Ngoc Kim Nguyen,
Bella Poduska,
Mia Franks
et al.

Abstract: Copper is an essential trace metal for biological processes in humans and animals. A low level of copper detection at physiological pH using fluorescent probes is very important for in vitro applications, such as the detection of copper in water or urine, and in vivo applications, such as tracking the dynamic copper concentrations inside cells. Copper homeostasis is disrupted in neurological diseases like Alzheimer’s disease, and copper forms aggregates with amyloid beta (Ab42) peptide, resulting in senile pla… Show more

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