A Cost-Effectiveness Analysis of Screening for Hepatitis B Surface Antigen in India

Bj, McNeil; Ra, Dudley; Hoop, Bartjan de; Metz, C.A.; Thompson, Mark S.; Sj, Adelstein

doi:10.1177/0272989x8100100405

Cited by 7 publications

(2 citation statements)

References 4 publications

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“…With one-way analysis, each uncertainty component of the evaluation is varied individually, while the others are held at their baseline values, in order to establish the separate effect of each component on the results of the evaluation. For example, in a cost-effectiveness analysis of a screening programme for hepatitis B surface antigen in India, 64 the authors carried out a one-way sensitivity analysis on all variables, which they illustrated graphically by plotting the effectiveness and cost results against a range of each of the uncertain variables. It has been argued that a set of one-way analyses such as these may be sufficient if each of the uncertain variables is independent of the others.…”

Section: Simple Sensitivity Analysismentioning

confidence: 99%

“…In the analysis of a screening programme for hepatitis B surface antigen referred to above, 64 the authors reported, for each variable in their model, a partial derivative which, when multiplied by a change in a given parameter, generated the impact on costs and effectiveness results. They also suggested an alternative measure based on elasticities that can be applied when it is not possible to calculate partial derivatives.…”

Section: Simple Sensitivity Analysismentioning

confidence: 99%

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Handling uncertainty when performing economic evaluation of healthcare interventions.

Briggs¹,

Gray²

1999

Health Technology Assessment

311

218

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T he overall aim of the NHS R&D Health Technology Assessment (HTA) programme is to ensure that high-quality research information on the costs, effectiveness and broader impact of health technologies is produced in the most efficient way for those who use, manage and work in the NHS. Research is undertaken in those areas where the evidence will lead to the greatest benefits to patients, either through improved patient outcomes or the most efficient use of NHS resources. The Standing Group on Health Technology advises on national priorities for health technology assessment. Six advisory panels assist the Standing Group in identifying and prioritising projects. These priorities are then considered by the HTA Commissioning Board supported by the National Coordinating Centre for HTA (NCCHTA). This report is one of a series covering acute care, diagnostics and imaging, methodology, pharmaceuticals, population screening, and primary and community care. It was identified as a priority by the Methodology Panel and funded as project number 93/48/07. The views expressed in this publication are those of the authors and not necessarily those of the Standing Group, the Commissioning Board, the Panel members or the Department of Health. The editors wish to emphasise that funding and publication of this research by the NHS should not be taken as implicit support for the recommendations for policy contained herein. In particular, policy options in the area of screening will be considered by the National Screening Committee. This Committee, chaired by the Chief Medical Officer, will take into account the views expressed here, further available evidence and other relevant considerations. Reviews in Health Technology Assessment are termed 'systematic' when the account of the search, appraisal and synthesis methods (to minimise biases and random errors) would, in theory, permit the replication of the review by others.

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Section: Simple Sensitivity Analysismentioning

confidence: 99%

Section: Simple Sensitivity Analysismentioning

confidence: 99%

Handling uncertainty when performing economic evaluation of healthcare interventions.

Briggs¹,

Gray²

1999

Health Technology Assessment

311

218

View full text Add to dashboard Cite

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Uncertainty in the economic evaluation of health care technologies: The role of sensitivity analysis

1994

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Given the increased use of economic evaluation to inform decision making in the health service, it is particularly important that the research methods used are critically assessed and, where possible, improved. The systematic handling of uncertainty in economic evaluation is an important area that remains methodologically underdeveloped. With the increased use of the clinical trial as a vehicle for economic evaluation, there has been recent interest in how the statistical methods routinely employed to handle uncertainty in clinical research might be applied to economic evaluation. This paper reviews the types of uncertainty that exist in economic evaluation and argues that some forms of uncertainty are not amenable to statistical methods. Sensitivity analysis is not a single approach but can take a number of different forms. The different types of sensitivity analysis are reviewed, with an indication of their strengths and weaknesses in relation to the different types of uncertainty in economic evaluation.

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Strategic investment in preventive health care: Quantitative modelling for programme selection and resource allocation

Heidenberger

1996

OR Spektrum

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A Cost-Effectiveness Analysis of Screening for Hepatitis B Surface Antigen in India

Cited by 7 publications

References 4 publications

Handling uncertainty when performing economic evaluation of healthcare interventions.

Handling uncertainty when performing economic evaluation of healthcare interventions.

Uncertainty in the economic evaluation of health care technologies: The role of sensitivity analysis

Strategic investment in preventive health care: Quantitative modelling for programme selection and resource allocation

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