A cross-sectional study on the drug usage of insomnia in the Chinese medicine hospital in Long gang, Shenzhen

Abstract

IntroductionInsomnia was widely distributed among the population, and it was a risk factor for many diseases. To evaluate the condition of usage of drugs in Chinese hospital of Longgang, Shenzhen, we carried this cross-sectional research. We extracted the information of drug usage, symptoms of patients by R software (version 4.0.2) from Hospital Information System (HIS). The research was registered in Chinese Clinical Trial Registry, ChiCTR2000040703.MethodsA retrospective, cross-sectional study was conducted in Shenzhen Hospital of Beijing University of Chinese Medicine (Long Gang). Insomnia patients from Jan 1, 2016 to Nov 10, 2020 were included to cross-sectional study. We analyzed the basic information, the condition of drug usage and the relation of symptoms and drug usage by R software (version 4.0.2).ResultsTotally 9439 patients were included in the study. The average age of these patients was 45.81years (SD 13.97 years). Anxiety, dreaminess, dizzy, palpitation, headache, thirsty, weakness, chest distress, annoyance, abdominal distension, bad moods, difficulty falling asleep and bitter taste were core symptoms of insomnia. Totally 14256 times (67.65%) patients received drug prescription and more than one insomnia drug was administered in 8355 patients. The 10 most used drugs ranged from more to less were Estazolam (29.99%), Zaoren Anshen Capsule (15.50%), Oryzanol (14.82%), Diazepam (14.51%), Flupentixol and Melitracen (14.30%), Alprazolam (8.12%), Zolpidem Tartrate (5.29%), Vitamin B6 (4.76%), Sertraline (4.03%), Clonazepam (2.97%). ConclusionThe drug usage for insomnia in the Chinese medicine hospital in Long gang, Shenzhen were mainly included benzodiazepines, nonbenzodiazepines, Chinese patent medicines, anti-anxiety and anti-depression drugs, Oryzanol and Vitamin B6. The usage of Oryzanol and Vitamin B6 should be abused in Chinese medicine hospital, and the usage of Chinese medicine should be more rigorously evaluated. The nonbenzodiazepines should be promoted and broader understood in Chinese medicine hospital in Longgang, Shenzhen.