A cross-sectional survey to study the relationship of periodontal disease with cardiovascular disease, respiratory disease, and diabetes mellitus

Abstract

Background:Periodontal deterioration has been reported to be associated with systemic diseases such as cardiovascular disease (CVD), diabetes mellitus, respiratory disease, liver cirrhosis, bacterial pneumonia, nutritional deficiencies, and adverse pregnancy outcomes.Aim:The present study assessed the periodontal disease among patients with systemic conditions such as diabetes, CVD, and respiratory disease.Materials and Methods:The study population consisted of 220 patients each of CVD, respiratory disease, and diabetes mellitus, making a total of 660 patients in the systemic disease group. A control group of 340 subjects were also included in the study for comparison purpose. The periodontal status of the patients with these confirmed medical conditions was assessed using the community periodontal index of treatment needs (CPITNs) index.Results:The prevalence of CPITN code 4 was found to be greater among the patients with respiratory disease whereas the mean number of sextants with score 4 was found to be greater among the patients with diabetes mellitus and CVD. The treatment need 0 was found to be more among the controls (1.18%) whereas the treatment need 1, 2, and 3 were more among the patients with respiratory disease (100%, 97.73%, and 54.8%), diabetes mellitus (100%, 100% and 46.4%), and CVD (100%, 97.73%, and 38.1%), in comparison to the controls (6.18%).Conclusion:From the findings of the present study, it can be concluded that diabetes mellitus, CVD, and respiratory disease are associated with a higher severity of periodontal disease.

Periodontal disease increases the risk for onset of systemic comorbidities in dental hospital attendees: An 18‐year retrospective cohort study

“…Currently, there are no reports on the link of periodontal disease with overall profile of common comorbidities. Several recent studies show that the severity of periodontal destruction is related to multiple systemic conditions, respectively . Other studies deal with the interconnection of one specific comorbidity (e.g.…”

“…Several recent studies show that the severity of periodontal destruction is related to multiple systemic conditions, respectively. [39][40][41][42] Other studies deal with the interconnection of one specific comorbidity (e.g. CVD) to periodontal status with adjustment of other comorbidities as confounders.…”

In Vivo Assessments of Minocycline combined Hyaluronic Acid-mediated Ultrasound Therapy of Infected Wound in Rats

“…About one-half of the adult population suffers from moderate to severe periodontal diseases that are also potentially associated with diabetes mellitus [1]. The hyperglycemic environment promotes the expression of toll-like receptors in periodontal tissues, making diabetic patients more susceptible to periodontitis [2].…”

“…Intergroup analysis (ND and D groups) showed greater bone loss in the ND group treated with SRP compared to the D group treated with SRP+SDT.DiscussionPg, as the major pathogenic microorganism, plays an important role in promoting the development and progression of periodontal disease[8]. Previous studies have reported that HMME combined with laser or ultrasound has an antimicrobial effect on whether Gram-positive or Gram-negative bacteria, such as MRSA, Escherichia coli1 2…”

Embracing Change In Dental Practice To Deliver Better Health Outcomes- A Type 2 Diabetes Screening and Oral Health Pilot Program

“…Oral disease, caries [5][6][7] and periodontal disease [6,[8][9][10] are associated with diabetes. Hyperglycaemia over a long period of time and glucose variability may result in chronic inflammation that affects the immune system.…”