A decade of thyroidology

Perros, Petros

doi:10.1007/s42000-018-0068-7

Cited by 3 publications

(2 citation statements)

References 49 publications

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“…Novel treatments that are currently being explored include the use of selenium, small-molecule ligand antagonists for the TSH receptor stimulatory antibodies and the use of teprotumumab (an IGF-1 receptor blocker), tocilizumab (IL-6 receptor antagonist), and rituximab (Anti-CD20 monoclonal antibody), especially for corticosteroids resistant cases [28][29][30] .…”

Section: Treatment and Prognosismentioning

confidence: 99%

Thyroid disease and associated ophthalmopathy

Concepción¹,

Marte²,

Escalante³

2022

HGMX

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Thyroid-associated ophthalmopathy is a complex pathology most of the time accompanying Graves' disease, also present in other thyroid states, such as Hashimoto's hypothyroidism and euthyroid states. The term Grave's disease associated ophthalmopathy can be misleading as it does not include all thyroid states associated to this eye condition. Its pathophysiology includes complex autoimmune mechanisms associated with fibroblasts, T-lymphocytes, myocytes, thyroid cells, adipocytes, and pro-inflammatory molecules, leading to several changes in the orbital content, including limitation of space, functional impairment, and complications secondary to the initial process. Reviewing its diagnostic methods and treatments is necessary due to new insights into the pathophysiology. The complexity of its pathogenesis is accompanied by a practical assessment and classification that allows clinicians to obtain significant amount of success when treating it.

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Section: Treatment and Prognosismentioning

confidence: 99%

Thyroid disease and associated ophthalmopathy

Concepción¹,

Marte²,

Escalante³

2022

HGMX

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“…Diseases of the thyroid gland, leading to disruptions in the functioning of the entire body, take first place among diseases of the endocrine system. Consequently, new means and treatment options occupy an important place in the study of this problem [6][7][8]. The direction of studying new medicinal plants capable of accumulating iodine is considered promising.…”

Section: Introductionmentioning

confidence: 99%

Compensation for iodine deficiency conditions with drugs based on duckweed substrate

Sadulaev,

Usmanova,

Tataev

et al. 2023

BIO Web Conf.

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Currently, one of the important problems for the entire population of Russia is the problem of iodine deficiency. This pathology is of significant relevance for residents of the North Caucasus. The growth of the goiter epidemic was provoked by the abolition of iodine prophylaxis from salt iodization in the 70s of the 20th century. In order to avoid an increase in morbidity, they began to develop and introduce not only iodine-containing preparations of chemical origin, but also medicines developed from iodine-containing plants acquired particular relevance. Iodine found in plants is well absorbed by the human body, as it is close to it in biological structure. The most common and generally accepted medicinal plants for the treatment of iodine deficiency conditions are white cinquefoil, sugar kelp and bladderwrack. These plants have a high content of natural iodine, but at the same time, the problem is a significant limitation of raw materials. That is why the search for new plant substrates with a high iodine content and the possibility of restoring iodine deficiency states is so important.

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