2022
DOI: 10.1002/smll.202106172
|View full text |Cite
|
Sign up to set email alerts
|

A Dual‐Cross‐Linked Hydrogel Patch for Promoting Diabetic Wound Healing

Abstract: Disorder of these physiological processes causes persistent inflammation and dys functional epithelial formation. Even tually, it leads to wound nonunion and increases the risk of infection. [2] Accu mulating evidence indicates that for accelerating diabetic wound healing, it is crucial to avoid excessive inflammation, including secretion of inflammatory fac tors in chronic wounds and inappropriate macrophage differentiation. [3] The clas sically activated macrophages (M1) and alternatively activated macrophag… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

1
82
0

Year Published

2022
2022
2024
2024

Publication Types

Select...
10

Relationship

1
9

Authors

Journals

citations
Cited by 149 publications
(83 citation statements)
references
References 70 publications
1
82
0
Order By: Relevance
“…Hence, this suggests that AgNPs do not contribute to the changes in the porous structure of the hydrogel networks, largely due to the nature of ultrasmall particles accompanied by higher stability of AgNPs@MSA in a complex environment. A similar type of porous structure was also observed in previous studies, contributing to higher loading capacity and water uptake resulting in rapid swelling and deswelling as well as high biocompatibility. , The uniformly distributed porous structure is highly useful for efficient mobility of nanoparticles while playing an important role in rapidly sensing the environmental stimuli, triggering the prompt release of therapeutics including AgNPs.…”
Section: Resultssupporting
confidence: 74%
“…Hence, this suggests that AgNPs do not contribute to the changes in the porous structure of the hydrogel networks, largely due to the nature of ultrasmall particles accompanied by higher stability of AgNPs@MSA in a complex environment. A similar type of porous structure was also observed in previous studies, contributing to higher loading capacity and water uptake resulting in rapid swelling and deswelling as well as high biocompatibility. , The uniformly distributed porous structure is highly useful for efficient mobility of nanoparticles while playing an important role in rapidly sensing the environmental stimuli, triggering the prompt release of therapeutics including AgNPs.…”
Section: Resultssupporting
confidence: 74%
“…The responsiveness to UV irradiation for gelation was consistent with the previous research on GelMA-based injectable hydrogels. 39,40 G 0 and G 00 of the PSBDA@AgNPs-GelMA-PVA hydrogel were further monitored as a function of shear frequency. As demonstrated in Fig.…”
Section: Enhanced Stability Of Psbda@agnpsmentioning
confidence: 99%
“…Ascribing to the low-cost and abundant resource, hydrogels derived from natural proteins and peptides have been extensively used from the bench to the bedside recently. Natural elements offer unique pharmacological performance to elevate the function of stem cells and accelerate wound healing through their bioactive factors ( Bo et al, 2020 ; Wu T. et al, 2021 ; Liu et al, 2022 ). Egg white (EW) is an easily available natural nutriment that is essentially a diverse protein complex such as ovalbumin, ovotransferrin and lysozyme ( Mann and Mann, 2011 ).…”
Section: Introductionmentioning
confidence: 99%