A dual-mode nanosensor based on carbon quantum dots and gold nanoparticles for discriminative detection of glutathione in human plasma

Shi, Yupeng; Pan, Yi; Zhang, Heng; Zhang, Zhaomin; Li, Meijin; Yi, Changqing; Yang, Mengsu

doi:10.1016/j.bios.2013.12.038

Cited by 292 publications

(102 citation statements)

References 46 publications

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“…Shi and coworkers reported a dual-mode nanosensor with both colorimetric and fluorometric readuot based on CDs and gold nanoparticles (AuNPs) for discriminative detection of GSH in the presence of cysteine and homocysteine [259]. The used CDs had plenty of amine groups on the surfaces, while AuNPs have a large quantity of carboxylic groups.…”

Section: Glutathione Detectionmentioning

confidence: 99%

“…In brief, a molecularly templated polymer was prepared by electropolymerization of MR-doped o-phenylenediamine as a functional [60]. b Schematic principle of GSH detection by using the dual-mode nanosensor with both colorimetric and fluorometric readout [259] monomer and dimethoate as the template. After a careful elution with methanol, the molecularly imprinted polymer was subsequently immersed in dimethoate solution to mask all the vacant binding cavities and incubated in CDs-labeled dimethoate solution.…”

Section: Organic Pollutants Detectionmentioning

confidence: 99%

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Carbon Based Dots and Their Luminescent Properties and Analytical Applications

Dong

Jian-Hua

Chi

2016

Carbon Nanoparticles and Nanostructures

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Carbon based dots (CDs) composed of sp 2 carbon structures and surface functional groups are a new kind of carbon nanomaterials, exhibiting unique luminescent properties due to the quantum confinement and edge effects. This chapter introduces CDs in detail from their synthetic strategies, morphological and structural characteristics, luminescent properties and mechanisms, and sensing applications. The synthesis methods are summarized as "top-down" and "bottomup" approaches. Luminescent properties discussed include photoluminescence, upconversion luminescence, chemiluminescence, electrochemiluminescence. Sensing applications mainly refer to the chemical and biological sensors based on the luminescent properties of CDs. This chapter provides an overview of the research field and gives future perspectives for developing the exciting materials.

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Section: Glutathione Detectionmentioning

confidence: 99%

Section: Organic Pollutants Detectionmentioning

confidence: 99%

Carbon Based Dots and Their Luminescent Properties and Analytical Applications

Dong

Jian-Hua

Chi

2016

Carbon Nanoparticles and Nanostructures

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“…Since carboxyl groups are able to facilitate the dehydration and carbonization, CA is frequently used as carbon source to prepare CQDs through pyrolysis methods [30,31,[34][35][36][37]. It has been reported that the addition of surface-passivation reagents especially amine molecules during the pyrolysis would significantly increase the quantum yield of the resultant CQDs [38].…”

Section: Synthesis and Characterization Of Cqd-dtpa-gdmentioning

confidence: 99%

Facile synthesis of gadolinium (III) chelates functionalized carbon quantum dots for fluorescence and magnetic resonance dual-modal bioimaging

Shi

Pan

Zhong

et al. 2015

Carbon

Self Cite

105

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“…To increase the accuracy and efficiency of 16S rRNA detection, several methods have been developed. Over the last decade, label-free biosensors have been used for rapid and sensitive bimolecular detection in the monitoring of the environment, controlling of food products and their use in the medical diagnostics [6,7,8,9,10,11]. Among them, the label-free biosensor based on the hybridization between capture DNA and target DNA enables direct, sensitive and rapid detection of DNA without target amplification [12,13,14].…”

Section: Introductionmentioning

confidence: 99%

Efficient Fluorescence Resonance Energy Transfer between Quantum Dots and Gold Nanoparticles Based on Porous Silicon Photonic Crystal for DNA Detection

Zhang

Jia

2017

Sensors

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A novel assembled biosensor was prepared for detecting 16S rRNA, a small-size persistent specific for Actinobacteria. The mechanism of the porous silicon (PS) photonic crystal biosensor is based on the fluorescence resonance energy transfer (FRET) between quantum dots (QDs) and gold nanoparticles (AuNPs) through DNA hybridization, where QDs act as an emission donor and AuNPs serve as a fluorescence quencher. Results showed that the photoluminescence (PL) intensity of PS photonic crystal was drastically increased when the QDs-conjugated probe DNA was adhered to the PS layer by surface modification using a standard cross-link chemistry method. The PL intensity of QDs was decreased when the addition of AuNPs-conjugated complementary 16S rRNA was dropped onto QDs-conjugated PS. Based on the analysis of different target DNA concentration, it was found that the decrease of the PL intensity showed a good linear relationship with complementary DNA concentration in a range from 0.25 to 10 μM, and the detection limit was 328.7 nM. Such an optical FRET biosensor functions on PS-based photonic crystal for DNA detection that differs from the traditional FRET, which is used only in liquid. This method will benefit the development of a new optical FRET label-free biosensor on Si substrate and has great potential in biochips based on integrated optical devices.

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A dual-mode nanosensor based on carbon quantum dots and gold nanoparticles for discriminative detection of glutathione in human plasma

Cited by 292 publications

References 46 publications

Carbon Based Dots and Their Luminescent Properties and Analytical Applications

Carbon Based Dots and Their Luminescent Properties and Analytical Applications

Facile synthesis of gadolinium (III) chelates functionalized carbon quantum dots for fluorescence and magnetic resonance dual-modal bioimaging

Efficient Fluorescence Resonance Energy Transfer between Quantum Dots and Gold Nanoparticles Based on Porous Silicon Photonic Crystal for DNA Detection

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