A dual-mode ratiometric fluorescence and smartphone-assisted colorimetric sensing platform based on bifunctional Fe,Co-CQD for glucose analysis at physiological pH

Wang, Linjie; Zheng, Shujun; Lü, Ling; Li, Caolong; Wang, Fei

doi:10.1016/j.aca.2022.340701

Cited by 21 publications

(5 citation statements)

References 35 publications

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“…Based on the inner filter and dynamic quenching effect, the proposed FL/colorimetry/smartphone method was applied to determine metoprolol tartrate (MPT) in serum and urine samples with satisfactory results. Wang et al [101] prepared the bifunctional iron and cobalt co-doped carbon quantum dot (Fe,Co-CQD) as a ratiometric FL/colorimetric sensing platform with good optical properties and peroxidasemimetic catalytic activity. This dual-mode sensing platform was constructed for the analysis of glucose at physiological pH with LODs of 0.167 µmol/L by FL and 1.126 µmol/L by colorimetry.…”

Section: Fl-based Multi-mode Methodsmentioning

confidence: 99%

Recent Advances in the DNA-Mediated Multi-Mode Analytical Methods for Biological Samples

Huang

Zhang

2023

Biosensors

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DNA-mediated nanotechnology has become a research hot spot in recent decades and is widely used in the field of biosensing analysis due to its distinctive properties of precise programmability, easy synthesis and high stability. Multi-mode analytical methods can provide sensitive, accurate and complementary analytical information by merging two or more detection techniques with higher analytical throughput and efficiency. Currently, the development of DNA-mediated multi-mode analytical methods by integrating DNA-mediated nanotechnology with multi-mode analytical methods has been proved to be an effective assay for greatly enhancing the selectivity, sensitivity and accuracy, as well as detection throughput, for complex biological analysis. In this paper, the recent progress in the preparation of typical DNA-mediated multi-mode probes is reviewed from the aspect of deoxyribozyme, aptamer, templated-DNA and G-quadruplex-mediated strategies. Then, the advances in DNA-mediated multi-mode analytical methods for biological samples are summarized in detail. Moreover, the corresponding current applications for biomarker analysis, bioimaging analysis and biological monitoring are introduced. Finally, a proper summary is given and future prospective trends are discussed, hopefully providing useful information to the readers in this research field.

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Section: Fl-based Multi-mode Methodsmentioning

confidence: 99%

Recent Advances in the DNA-Mediated Multi-Mode Analytical Methods for Biological Samples

Huang

Zhang

2023

Biosensors

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“…Wang et al [38] have developed a glucose-sensing technique that combines dual-mode ratiometric fluorescence and colorimetric detection using a smartphone. Their approach is based on mimicking the activity of FeCo by using Fe,Co-doped carbon nanoparticles (Fe,Co-CQD) to demonstrate peroxidase-like activity toward the substrate o-phenylenediamine (OPD)-a non-fluorescence reagent-under alkaline conditions.…”

Section: Applications Of Bio-chemical Optical Sensors Using a Smartphonementioning

confidence: 99%

“…Glucose Portable kit-smartphone-assisted fluorescent/colorimetric device. 0.093 µM/0.437 µM [38] Glucose, uric acid, and cholesterol…”

Section: Ambient Light Sensor Of Smartphone-based Biosensorsmentioning

confidence: 99%

Smartphone-Based Portable Bio-Chemical Sensors: Exploring Recent Advancements

Bui,

Thangavel,

Sharipov

et al. 2023

Chemosensors

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Traditionally, analytical chemistry and diagnosis relied on wet laboratories and skilled professionals utilizing sophisticated instruments for sample handling and analysis. However, with the development of novel materials and sensing techniques, there has been a significant shift towards the use of standalone sensors, allowing tests to be conducted on-site or even in real time, leading to cost- and time-efficiency. With their widespread adoption globally, smartphones have emerged as an ideal platform for such sensors, boasting extensive sensor capabilities, advanced processing power, and communication functionalities. Smartphone-based assays make use of optical and electrochemical sensors, utilizing built-in cameras, ambient light sensors, and other features for optical sensing, while the micro-USB port, Bluetooth, and wireless connection facilitate data transmission and analog voltage application for electrochemical sensing. Previous overview papers have explored smartphone-based sensing in specific domains; this review provides a comprehensive examination of recent advancements in smartphone-based sensors, encompassing both optical and electrochemical sensing methods. The review provides the fundamental principles of these sensors and their implementation using smartphones, showcases recent applications, and presents innovative designs that take advantage of the inherent functionalities and sensor capabilities of smartphones. The review concludes by offering an outlook on the prospects of smartphone-based sensing and includes a reflective section emphasizing the potential impact of sensors in chemical and biological analyses. This comprehensive resource aims to provide information to researchers and practitioners interested in using smartphones for cutting-edge analytical methodologies.

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“…However, the modification of GOx structure through chemical reactions and the shielding of catalytic sites after modification pose challenges to its further development [ 146 ]. DMSN, with its large pore size, can easily accommodate large proteins during preparation, enabling increased loading of GOx [ 147 ]. Under normal physiological conditions, DMSN ensures that GOx and metal catalysts maintain excellent catalytic performance while facilitating the proper diffusion of small molecule products and substrates.…”

Section: Nps For Delivering G-mmentioning

confidence: 99%

Glucose oxidase and metal catalysts combined tumor synergistic therapy: mechanism, advance and nanodelivery system

Fu,

Sun,

Wang

et al. 2023

J Nanobiotechnol

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Cancer has always posed a significant threat to human health, prompting extensive research into new treatment strategies due to the limitations of traditional therapies. Starvation therapy (ST) has garnered considerable attention by targeting the primary energy source, glucose, utilized by cancer cells for proliferation. Glucose oxidase (GOx), a catalyst facilitating glucose consumption, has emerged as a critical therapeutic agent for ST. However, mono ST alone struggles to completely suppress tumor growth, necessitating the development of synergistic therapy approaches. Metal catalysts possess enzyme-like functions and can serve as carriers, capable of combining with GOx to achieve diverse tumor treatments. However, ensuring enzyme activity preservation in normal tissue and activation specifically within tumors presents a crucial challenge. Nanodelivery systems offer the potential to enhance therapy effectiveness by improving the stability of therapeutic agents and enabling controlled release. This review primarily focuses on recent advances in the mechanism of GOx combined with metal catalysts for synergistic tumor therapy. Furthermore, it discusses various nanoparticles (NPs) constructs designed for synergistic therapy in different carrier categories. Finally, this review provides a summary of GOx-metal catalyst-based NPs (G-M) and offers insights into the challenges associated with G-M therapy, delivery design, and oxygen (O2) supply.

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A dual-mode ratiometric fluorescence and smartphone-assisted colorimetric sensing platform based on bifunctional Fe,Co-CQD for glucose analysis at physiological pH

Cited by 21 publications

References 35 publications

Recent Advances in the DNA-Mediated Multi-Mode Analytical Methods for Biological Samples

Recent Advances in the DNA-Mediated Multi-Mode Analytical Methods for Biological Samples

Smartphone-Based Portable Bio-Chemical Sensors: Exploring Recent Advancements

Glucose oxidase and metal catalysts combined tumor synergistic therapy: mechanism, advance and nanodelivery system

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