A feasibility study of dynasplint to prevent trismus in head and neck cancer patients receiving radiation therapy.

Zatarain, Lauren Azure; Smith, Clayton; Dietrich, Mary S.; Niermann, Kenneth J.; Gilbert, Jill; Hadziahmetovic, Mersiha; Ridner, Sheila H.; Murphy, Barbara A.

doi:10.1200/jco.2014.32.15_suppl.e20676

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“…A total of 19 of 964 identified references satisfied the eligibility criteria of the present synthesis ( Figure 1 ). The 19 references reported 11 RCTs from Brazil ( n = 90), China ( n = 104), Denmark ( n = 100), England ( n = 71), the Netherlands ( n = 55), Sweden ( n = 66), Taiwan ( n = 68), and the United States ( n = 258) between 2001 and 2018 [ 8 , 9 , 15 , 16 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 ].…”

Section: Resultsmentioning

confidence: 99%

Exercise for Trismus Prevention in Patients with Head and Neck Cancer: A Network Meta-Analysis of Randomized Controlled Trials

et al. 2022

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A common side effect of managing head and neck cancer is trismus, which devastates patients’ quality of life. The purpose of this study was to investigate prophylactic exercise interventions for preventing trismus and difficulty in mouth opening in head and neck cancer. Five databases were searched for randomized controlled trials. Network meta-analysis was performed with risk ratio (RR) or mean difference (MD) with 95% confidence interval (CI). This study finally included 11 randomized controlled trials (n = 805). Trismus risk in patients who received exercise with phone call follow up (E + P) was significantly lower than those received usual care (RR = 0.42; 95% CI: 0.29 to 0.61) and exercise alone (RR = 0.33; 95% CI: 0.18 to 6.22). Mouth opening in usual care was significantly lower than in the tri-integrated strategy group (MD = 15.22; 95% CI: 8.88 to 21.56). Exercise is recommended for preserving mouth opening distance in patients with head and neck cancer. Tri-integrated strategies could be an effective method for preventing trismus.

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