A feasibility study on the use of arrays of discrete SiPMs for MR compatible LYSO readout using Monte Carlo simulation

Aguiar, Pablo; Iglesias, A.; Couce, B.; Lois, Cristina

doi:10.1088/1748-0221/7/06/p06002

Cited by 9 publications

(7 citation statements)

References 20 publications

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“…Note that good matching between simulated and experimental data for the optical tracking process has been previously reported with GATE simulations (LoMeo et al 2009). In particular, an optical transport model with GATE for monolithic crystals coupled to an MA-PMT (similar to the detector module used for the present work) was previously validated by our group (Aguiar et al 2012).…”

Section: The Analytical Plus Monte Carlo Srm (Amc-srm)supporting

confidence: 73%

The performance of a hybrid analytical-Monte Carlo system response matrix in pinhole SPECT reconstruction

et al. 2014

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It is well-known that in pinhole SPECT (single-photon-emission computed tomography), iterative reconstruction methods including accurate estimations of the system response matrix can lead to submillimeter spatial resolution. There are two different methods for obtaining the system response matrix: those that model the system analytically using an approach including an experimental characterization of the detector response, and those that make use of Monte Carlo simulations. Methods based on analytical approaches are faster and handle the statistical noise better than those based on Monte Carlo simulations, but they require tedious experimental measurements of the detector response. One suggested approach for avoiding an experimental characterization, circumventing the problem of statistical noise introduced by Monte Carlo simulations, is to perform an analytical computation of the system response matrix combined with a Monte Carlo characterization of the detector response. Our findings showed that this approach can achieve high spatial resolution similar to that obtained when the system response matrix computation includes an experimental characterization. Furthermore, we have shown that using simulated detector responses has the advantage of yielding a precise estimate of the shift between the point of entry of the photon beam into the detector and the point of interaction inside the detector. Considering this, it was possible to slightly improve the spatial resolution in the edge of the field of view.

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Section: The Analytical Plus Monte Carlo Srm (Amc-srm)supporting

confidence: 73%

The performance of a hybrid analytical-Monte Carlo system response matrix in pinhole SPECT reconstruction

et al. 2014

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“…They conclude that the LYSO background should not deteriorate the performance of a SPECT system. Related to this, Monte-Carlo simulations were done to evaluate an MR-compatible PET or SPECT detector based on LYSO and Silicon Photomultipliers (SiPMs) (Aguiar et al 2012). Background measurements were also done by Liang et al (2009) to evaluate a gamma camera that consists of pixelated LYSO (pixel size 2 mm × 2 mm) for positron and scinti-mammography.…”

Section: Introductionmentioning

confidence: 99%

A high resolution SPECT detector based on thin continuous LYSO

2013

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Single-photon emission computed tomography (SPECT) detectors with improved spatial resolution can be used to build multi-pinhole SPECT systems that have a higher sensitivity or a higher spatial resolution. In order to improve the spatial resolution we investigate the performance of a 2 mm thick continuous Lutetium Yttrium Orthosilicate (LYSO) scintillator and compare it to the performance of a 5 mm thick continuous NaI(Tl) scintillator. The advantages of LYSO are its high stopping power and its non-hygroscopicity. Drawbacks are the lower light output and the intrinsic radioactivity. The hypothesis of this study is that such a thin LYSO scintillator will have a small light spread and, as a consequence, will also have an improved spatial resolution when coupled to a Hamamatsu H8500 position sensitive photomultiplier tube. To optimize the spatial resolution and the useful detector area we used a mean nearest neighbor event-positioning method. Beam source measurements ((99m)Tc, 140 keV) were done to investigate the energy resolution and the spatial resolution of both detectors. The effect of the intrinsic radioactivity of the LYSO scintillator in the energy window was quantified. The mean energy resolution is 9.3% for the NaI(Tl) scintillator and 21.3% for the LYSO scintillator. The LYSO spectrum shows an X-ray escape peak which decreases the detection efficiency with 9.1%. The spatial resolution of the LYSO detector (0.93 mm full width at half maximum (FWHM)) is superior to the spatial resolution of the NaI(Tl) detector (1.37 mm FWHM). The intrinsic radioactivity in the energy window (42% window centered at 140 keV) is low (125.6 cps, 0.024 cps mm(-3)). LYSO is a promising scintillator for small-animal SPECT imaging, where spatial resolution is more important than energy resolution.

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“…The slab thickness reference value is 1.27 cm but larger values are considered. The selection of scintillator surface finish is based on a previous work showing the effect of high reflectivity and surface roughness [14]. The cm faces are rough surfaces, covered with highly reflective foil (3M Vikuiti ESR [15] with a reflectivity coef.…”

Section: A Description Of the Detector Modulementioning

confidence: 99%