A field trial using detomidine/ketamine for anaesthesia in the horse

Fisher, R. J.

doi:10.1111/j.1467-2995.1986.tb00334.x

Cited by 2 publications

(3 citation statements)

References 4 publications

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“…O pioneiro na aplicação de projeto de experimentos, aliado a métodos estatísticos, foi Ronald A. Fisher, cientista britânico, que em 1926 publicou uma pesquisa realizada na Rothamsted Experimental Station, instituto de pesquisas em agricultura, situada em Hertfordshire, Inglaterra (FISHER, 1926).…”

Section: Projeto De Experimentosunclassified

Modelagem E Otimização Da Vida De Dressadores Baseado Em Modelos Lineares Generalizados

CESÁRIO,

SANTOS,

SOUZA

et al. 2023

Anais Do Encontro Nacional De Engenharia De Produção

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XLIII ENCONTRO NACIONAL DE ENGENHARIA DE PRODUÇÃO"A contribuição da engenharia de produção para desenvolvimento sustentável das organizações: Cadeias Circulares, sustentabilidade e tecnologias" Fortaleza, Ceará, Brasil, 17 a 20 de outubro de 2023. XLIII ENCONTRO NACIONAL DE ENGENHARIA DE PRODUÇÃO"A contribuição da engenharia de produção para desenvolvimento sustentável das organizações: Cadeias Circulares, sustentabilidade e tecnologias" Fortaleza, Ceará, Brasil, 17 a 20 de outubro de 2023.

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Section: Projeto De Experimentosunclassified

Modelagem E Otimização Da Vida De Dressadores Baseado Em Modelos Lineares Generalizados

CESÁRIO,

SANTOS,

SOUZA

et al. 2023

Anais Do Encontro Nacional De Engenharia De Produção

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“…With its greater potency, and longer duration of action, detomidine has the potential to provide a superior surgical plane of anaesthesia. It has not gained popularity in this role, largely because of the poorer recovery scores reported with its use; however, the majority of studies comparing detomidine to other anaesthetic regimens have used a low number of horses in a non‐clinical setting …”

Section: Introductionmentioning

confidence: 99%

“…It has not gained popularity in this role, largely because of the poorer recovery scores reported with its use; however, the majority of studies comparing detomidine to other anaesthetic regimens have used a low number of horses in a non-clinical setting. [8][9][10][11][12][13] The aim of this study was to compare the anaesthetic characteristics of xylazine vs detomidine followed by co-induction with ketamine and midazolam for horses undergoing field castration in a clinical setting.…”

Section: Introductionmentioning

confidence: 99%

Comparison of xylazine and detomidine in combination with midazolam/ketamine for field castration in Quarter Horses

Smith¹,

Bass

Damone

et al. 2020

Equine Veterinary Journal

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Background The ideal field anaesthetic protocol for castration will offer an adequate duration and depth of anaesthesia using a single injection without compromising safety or recovery quality. Objectives The objective of this study was to compare intravenous (IV) xylazine and detomidine as sedatives in combination with midazolam and ketamine for induction of anaesthesia in horses undergoing field castration. Study design Randomised, blinded, clinical study. Methods Fifty‐seven male Quarter Horses were randomly assigned to receive xylazine (group X) (1.1 mg/kg bwt) or detomidine (group D) (0.03 mg/kg bwt) as premedication with midazolam (0.05 mg/kg bwt) and ketamine (2.2 mg/kg bwt) anaesthesia. Using simple descriptive scales, quality of sedation, induction, surgical conditions and recovery were scored by blinded observers. Induction, surgery, recovery time and time from induction to standing were recorded. Results There were a greater number of horses with lower sedation score in group D when compared with horses in group X at 5 minutes after the first dose of sedation (11.1%, 66.7% and 2.2% of horses from group D with sedation scores of 1, 2 and 3, vs 0%, 52% and 48% from group X, respectively, P = .05). A significant (P < .01) difference was found between surgical condition scores for group D (63%, 14.8%, 11.1% and 11.1% with surgery scores of 1, 2, 3 and 4, respectively) and group X (28%, 4%, 28% and 40%). Horses in Group D were less likely to require maintenance doses of ketamine (P = .05) with only 26% (7 of 27 horses) in this group requiring additional doses compared to 68% (17 of 25 horses) in group X. Recovery time in minutes (Group D: 24.74 ± 14.80, Group X: 13.08 ± 8.00; P < .01) and induction to standing time in minutes (Group D: 42.2 ± 13.8, Group X: 29.8 ± 8.2; P < .01) were significantly longer for horses in group D compared with group X. Main limitations Multiple surgeons and multiple blinded observers. Conclusions Detomidine as compared with xylazine as premedication results in good quality sedation and surgical conditions and prolonged surgical plane of anaesthesia, without significant differences in induction or recovery quality.

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A field trial using detomidine/ketamine for anaesthesia in the horse

Cited by 2 publications

References 4 publications

Modelagem E Otimização Da Vida De Dressadores Baseado Em Modelos Lineares Generalizados

Modelagem E Otimização Da Vida De Dressadores Baseado Em Modelos Lineares Generalizados

Comparison of xylazine and detomidine in combination with midazolam/ketamine for field castration in Quarter Horses

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