A first-generation EST RH comparative map of the porcine and human genome

Rink, Anette; Santschi, Elizabeth M.; Eyer, Katie M.; Roelofs, Benjamin; Heß, Markus; Godfrey, Myra; Karajusuf, Elif K.; Yerle, Martine M.; Milan, Denis; Beattie, Craig W.

doi:10.1007/s00335-002-2192-5

Cited by 80 publications

(71 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We conclude that the porcine A3 genes are located on the short arm of chromosome 5. Comparing maps of human and pig chromosomes (29,83; http://www.toulouse .inra.fr/lgc/pig/compare/compare.htm), we were able to underpin our results: the genomic region of Sus scrofa chromosome 5p14-p ter (where ter is telomere) is syntenic to Homo sapiens chromosome 22q12-q ter . The human A3 gene cluster is located on chromosome 22q13.1 (http://www.genome.ucsc.edu/).…”

Section: Resultsmentioning

confidence: 56%

Restriction of Porcine Endogenous Retrovirus by Porcine APOBEC3 Cytidine Deaminases

Dörrschuck

Fischer

Bravo³

et al. 2011

J Virol

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 56%

Restriction of Porcine Endogenous Retrovirus by Porcine APOBEC3 Cytidine Deaminases

Dörrschuck

Fischer

Bravo³

et al. 2011

J Virol

View full text Add to dashboard Cite

“…Interesting examples include the conserved homologs BTA12/HSA13, BTA19/HSA17, BTA24/HSA18, and BTAX/HSAX. HSA17 is a particularly interesting chromosome as it is fully conserved in most mammals studied to date: SSC12 in pig, E1 in cat, MMU11 in mouse, ECA11 in horse, and the h-arm of hm in shrew (Larkin et al 2000;Rink et al 2002;Waterston et al 2002;Chowdhary et al 2003;Menotti-Raymond et al 2003). The dog genome shows conservation of the distal part of HSA17p on CFA5, and the remainder of HSA17 on CFA9 (Guyon et al 2003).…”

Section: Second-generation Cattle-human Comparative Mapmentioning

confidence: 99%

A 1463 Gene Cattle–Human Comparative Map With Anchor Points Defined by Human Genome Sequence Coordinates

Wind¹,

Kata²,

Band³

et al. 2004

Genome Res.

139

View full text Add to dashboard Cite

A second-generation 5000 rad radiation hybrid (RH) map of the cattle genome was constructed primarily using cattle ESTs that were targeted to gaps in the existing cattle–human comparative map, as well as to sparsely populated map intervals. A total of 870 targeted markers were added, bringing the number of markers mapped on the RH5000 panel to 1913. Of these, 1463 have significant BLASTN hits (E < e–5) against the human genome sequence. A cattle–human comparative map was created using human genome sequence coordinates of the paired orthologs. One-hundred and ninety-five conserved segments (defined by two or more genes) were identified between the cattle and human genomes, of which 31 are newly discovered and 34 were extended singletons on the first-generation map. The new map represents an improvement of 20% genome-wide comparative coverage compared with the first-generation map. Analysis of gene content within human genome regions where there are gaps in the comparative map revealed gaps with both significantly greater and significantly lower gene content. The new, more detailed cattle–human comparative map provides an improved resource for the analysis of mammalian chromosome evolution, the identification of candidate genes for economically important traits, and for proper alignment of sequence contigs on cattle chromosomes.

show abstract

“…This work has been followed by RH mapping in a number of other animal species (McCarthy et al 1997;Priat et al 1998;Yerle et al 1998;Hawken et al 1999;Hukriede et al 1999;Kwok et al 1999;Murphy et al 1999;Vignaux et al 1999;Watanabe et al 1999). In addition to whole-genome RH mapping, other researchers have focused on mapping specific chromosomes and chromosomal regions in different species as well (Hoover and Floros 1998;Barendse et al 2000;Ozawa et al 2000;Liu et al 2002;Rink et al 2002).…”

mentioning

confidence: 99%

High-Resolution Radiation Hybrid Map of Wheat Chromosome 1D

Kalavacharla

Hossain

et al. 2006

Genetics

View full text Add to dashboard Cite

Physical mapping methods that do not rely on meiotic recombination are necessary for complex polyploid genomes such as wheat (Triticum aestivum L.). This need is due to the uneven distribution of recombination and significant variation in genetic to physical distance ratios. One method that has proven valuable in a number of nonplant and plant systems is radiation hybrid (RH) mapping. This work presents, for the first time, a high-resolution radiation hybrid map of wheat chromosome 1D (D genome) in a tetraploid durum wheat (T. turgidum L., AB genomes) background. An RH panel of 87 lines was used to map 378 molecular markers, which detected 2312 chromosome breaks. The total map distance ranged from $3,341 cR 35,000 for five major linkage groups to 11,773 cR 35,000 for a comprehensive map. The mapping resolution was estimated to be $199 kb/break and provided the starting point for BAC contig alignment. To date, this is the highest resolution that has been obtained by plant RH mapping and serves as a first step for the development of RH resources in wheat.

show abstract

A first-generation EST RH comparative map of the porcine and human genome

Cited by 80 publications

References 0 publications

Restriction of Porcine Endogenous Retrovirus by Porcine APOBEC3 Cytidine Deaminases

Restriction of Porcine Endogenous Retrovirus by Porcine APOBEC3 Cytidine Deaminases

A 1463 Gene Cattle–Human Comparative Map With Anchor Points Defined by Human Genome Sequence Coordinates

High-Resolution Radiation Hybrid Map of Wheat Chromosome 1D

Contact Info

Product

Resources

About