A flexible multimodal pulse sensor for wearable continuous blood pressure monitoring

Tian, Shuo; Wang, Liangqi; Zhu, Rong

doi:10.1039/d3mh01999c

Mater. Horiz.

2024

DOI: 10.1039/d3mh01999c

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A flexible multimodal pulse sensor for wearable continuous blood pressure monitoring

Shuo Tian,

Liangqi Wang,

Rong Zhu

Abstract: We propose a brand-new pressure sensing principle of human-skin’s piezo-thermic transduction, and develop a multisensory pulse sensor, thereby offering a human-skin transducer concept for wearable blood pressure monitoring with generalizability.

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Cited by 8 publications

References 41 publications

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Long‐Term Used Continuous Blood Pressure Monitoring via Personalized Object Transfer Learning Architecture Enhanced Triboelectric Pulse Sensors

Yao,

Liu,

et al. 2024

Adv Funct Materials

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Cardiovascular diseases remain the leading cause of global mortality, underscoring the importance of continuous blood pressure (BP) monitoring for early diagnosis and management. However, due to individual diversity and temporal variability of patients physiological characteristics, traditional BP models suffer from inaccuracies over time, hampering the practical applications of continuous BP monitoring devices. Herein, a personalized object transfer learning architecture (POTLA) enhanced triboelectric pulse sensor is developed for accurate long‐term used continuous BP monitoring. Utilizing inversed molding‐replica technique, a nanopillar triboelectric pulse sensor (NTPS) is fabricated, which possesses desirable linear response, high sensitivity, and remarkable durability. The NTPS can detect the detailed features of pulse signals for BP derivation. Further, the POTLA is proposed to enhanced the BP models, which effectively addresses the individual diversity and temporal variability, thereby minimizing errors in BP monitoring for long‐term use of the sensors. A 6‐month follow‐up test involving five participants demonstrates that the POTLA significantly optimizes the BP derivation, with accuracy improvements of >27%, comparing to the universal and personalized BP models without the POTLA. This POTLA‐coupled sensor strategy holds promise for enhancing precision medicine and advancing healthcare applications.

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Long‐Term Used Continuous Blood Pressure Monitoring via Personalized Object Transfer Learning Architecture Enhanced Triboelectric Pulse Sensors

Yao,

Liu,

et al. 2024

Adv Funct Materials

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Flexible Pressure, Humidity, and Temperature Sensors for Human Health Monitoring

Li,

Fang,

Wei

et al. 2024

Adv Healthcare Materials

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The rapid advancements in artificial intelligence, micro‐nano manufacturing, and flexible electronics technology have unleashed unprecedented innovation and opportunities for applying flexible sensors in healthcare, wearable devices, and human–computer interaction. The human body's tactile perception involves physical parameters such as pressure, temperature, and humidity, all of which play an essential role in maintaining human health. Inspired by the sensory function of human skin, many bionic sensors have been developed to simulate human skin's perception to various stimuli and are widely applied in health monitoring. Given the urgent requirements for sensing performance and integration of flexible sensors in the field of wearable devices and health monitoring, here is a timely overview of recent advances in pressure, humidity, temperature, and multi‐functional sensors for human health monitoring. It covers the fundamental components of flexible sensors and categorizes them based on different response mechanisms, including resistive, capacitive, voltage, and other types. Specifically, the application of these flexible tactile sensors in the area of human health monitoring is highlighted. Based on this, an extended overview of recent advances in dual/triple‐mode flexible sensors integrating pressure, humidity, and temperature tactile sensing is presented. Finally, the challenges and opportunities of flexible sensors are discussed.

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Wearable Single‐Electrode Capacitive Sensor with Large Penetration Depth for Intelligent Deep Tissue and Hemorrhage Monitoring

Cheng,

Kim,

White

et al. 2024

Advanced Sensor Research

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Monitoring deep tissue biometrics is crucial in various clinical settings, including internal hemorrhage. Although optical and impedance tomography techniques offer real‐time monitoring with minimal medical infrastructure, they still face challenges in accurately assessing deeper tissues in wearable formats. This study introduces a novel single‐electrode capacitive sensor designed to measure deep tissue capacitance changes caused by variations in dielectric constant and pressure. The sensor features a carbon nanotube‐paper composite (CPC) electrode integrated with a multi‐walled carbon nanotube (MWCNT)‐embedded foam. The CPC electrode, with its large surface area and high‐aspect‐ratio fibers, generates a high electric field for deeper tissue penetration, improving deep tissue monitoring performance. Penetration depth is characterized using surrogate tissue, heart, and lung models. Additionally, the integration of pressure‐sensitive MWCNT foam significantly enhances the sensitivity, enabling precise detection of regional blood volume and tissue displacement. The novel sensing mechanism is applied to detect internal hemorrhage in a porcine model. By employing a machine learning algorithm, the sensor accurately estimates the severity of internal hemorrhage, offering a noninvasive alternative to catheter‐based systems. This advancement lays the foundation for a real‐time wearable system that monitors deep tissue health metrics, such as blood volume, blood pressure, as well as heart and lung functions.

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A flexible multimodal pulse sensor for wearable continuous blood pressure monitoring

Abstract: We propose a brand-new pressure sensing principle of human-skin’s piezo-thermic transduction, and develop a multisensory pulse sensor, thereby offering a human-skin transducer concept for wearable blood pressure monitoring with generalizability.

Cited by 8 publications

References 41 publications

Long‐Term Used Continuous Blood Pressure Monitoring via Personalized Object Transfer Learning Architecture Enhanced Triboelectric Pulse Sensors

Long‐Term Used Continuous Blood Pressure Monitoring via Personalized Object Transfer Learning Architecture Enhanced Triboelectric Pulse Sensors

Flexible Pressure, Humidity, and Temperature Sensors for Human Health Monitoring

Wearable Single‐Electrode Capacitive Sensor with Large Penetration Depth for Intelligent Deep Tissue and Hemorrhage Monitoring

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