A fully automated effervescence-assisted switchable solvent-based liquid phase microextraction procedure: Liquid chromatographic determination of ofloxacin in human urine samples

Vakh, Christina; Pochivalov, Aleksei; Andruch, Vasiľ; Москвин, Л. Н.; Bulatov, Andrey

doi:10.1016/j.aca.2015.12.004

Cited by 100 publications

(30 citation statements)

References 32 publications

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“…It is a simple reaction to produce carbon dioxide which can help the dispersion of extraction solvents or adsorbents without additional energy. Similar works which tablet effervescence are served as dispersive force have been reported in recent years, applying to pesticide detection in various matrices, consisting juice, water and human urine samples . According to the advantage, it has tremendous potential to apply to on‐site analysis.…”

Section: Introductionmentioning

confidence: 77%

Tablet‐effervescence‐assisted dissolved carbon flotation for the extraction of four triazole fungicides in water by gas chromatography with mass spectrometry

Wei

Song

Nie

et al. 2016

J of Separation Science

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A pretreatment method named tablet-effervescence-assisted dissolved carbon flotation was introduced for the determination of four triazole fungicides in environmental water. In this method, the use of effervescent tablet composed of nontoxic sodium carbonate and sodium dihydrogen phosphate could generate CO in situ to assist the dispersion of extraction solvent and to accelerate mass transfer of target analytes. In addition, the simple phase separation simply based on the rising of low-density organic solvent from the aqueous phase was applied rather than the application of apparatus, which demonstrated the potential for on-site extraction in the field. The experimental variables, including the composition of effervescent tablets, amount of effervescent tablets, types and volume of extraction solvent, were investigated. Under the optimized conditions, the method showed good linearity for myclobutanil, tebuconazole, epoxiconazole, and difenoconazole in the range of 1-100 μg/L. The limits of detection and the limits of quantification were within the range of 0.15-0.26 and 0.49-0.86 μg/L, respectively. The obtained correlation coefficients varied from 0.997 to 0.999, and suitable enrichment factors were 422-589. The recoveries were 82.5-112.9% with relative standard deviations of 4.7-13.5%.

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Section: Introductionmentioning

confidence: 77%

Tablet‐effervescence‐assisted dissolved carbon flotation for the extraction of four triazole fungicides in water by gas chromatography with mass spectrometry

Wei

Song

Nie

et al. 2016

J of Separation Science

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“…Large amounts of CO 2 were produced through the reaction of H 2 SO 4 with Na 2 CO 3 , which increased the contact area between the nonanoic acid and extraction solution, resulting in improved extraction recovery. In addition, this method reduces errors associated with the collection of extraction media, with solidified fatty acids providing a highly efficient extraction agent to further improve extraction recovery [35]. Sample preparation time (23.9 min) was much shorter than SPE (150 h, 22 h, and 260 min) [11,22,23], SPME (55 min) [46], and TPATPS (14 h) [51].…”

Section: Comparison Of the Ea-sfam-sfo Methods With Othersmentioning

confidence: 99%

“…The solidification of nonanoic acid in an ice bath reduces experimental error caused by an inefficient collection of the extraction agent, but also avoids the need for specialized extraction devices, which simplifies operational steps and reduces experimental cost. The use of nonanoic acid, which solidifies upon chilling, further reduces complex matrix effects [34,35], resulting in improved accuracy and recovery.…”

Section: Comparison Of the Ea-sfam-sfo Methods With Othersmentioning

confidence: 99%

“…Shih et al (2015) [34] reported a novel fatty acid-based, in-tube dispersive liquid-liquid microextraction (FA-IT-DLLME) technique for the determination of alkylphenols in aqueous samples, which achieved high extraction recovery, short extraction times, and low extraction solvent requirements. To determine ofloxacin in human urine, Vakh et al (2016) [35] used hexanoic acid as an extraction solvent and developed a fully automated effervescencea s s i s t e d s w i t c h a b l e s o l v e n t -b a s e d l i qu i d p h a s e microextraction (EA-SS-LPME) with enhanced extraction recoveries achieved through bubbling of CO 2 to increase interaction with analytes.…”

Section: Introductionmentioning

confidence: 99%

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An effervescence-assisted switchable fatty acid-based microextraction with solidification of floating organic droplet for determination of fluoroquinolones and tetracyclines in seawater, sediment, and seafood

et al. 2018

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This study developed a new effervescence-assisted switchable fatty acid-based microextraction combined with solidification of a floating organic-droplet (EA-SFAM-SFO) for simple and rapid determination of fluoroquinolones and tetracyclines in seawater, sediment, and seafood. Five medium-chain fatty acids (pentanoic acid, hexanoic acid, heptanoic acid, octanoic acid, and nonanoic acid) were tested as an extraction solvent, given their ability to change between hydrophobic and hydrophilic forms by pH adjustment. As nonanoic acid had the highest extraction recovery (>92%) for the six antibiotics and the ability to transform from liquid to a solidified floating state at low temperature, it was selected as the optimum extraction solvent. The prominent advantages of the newly developed method are: (1) reaction between the procedures salt and fatty acid changed extraction solvent from the hydrophobic to hydrophilic state; (2) bubbling with CO greatly increased the contact area between fatty acid and analytes resulting in improved extraction recovery; and (3) solidification of the fatty acid at a low temperature provided good separation and avoided the use of specialized equipment. Single-factor screening and optimization of the main factors were conducted using Plackett-Burman design and central composite design, respectively. The main parameters were optimized as follows: 258 μL fatty acid, 406 μL HSO (98%), 3.9 min vortex time, and 354 μL NaCO (2 mol L1). Under optimized conditions, limits of detection were 0.007-0.113 μg L or μg kg and extraction recoveries were 82.2%-116.7% for six fluoroquinolone and tetracycline antibiotics in seawater, sediments, and seafood. The newly developed method combines the advantages of effervescence-assisted dispersion, hydrophobic/hydrophilic switchable solvent, and liquid/solid transition induced by low temperature. Overall, the new method is simple, quick, and environment-friendly with low detection limits and high recoveries. Thus, the newly developed method has excellent prospects for sample pretreatment and analysis of antibiotics in marine environmental and food samples. Graphical Abstract ᅟ.

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“…As an environmentally friendly solvent, medium-chain fatty acids have received increasing attention as a "green" solvent for sample pretreatment methods (Shih et al, 2015;Vakh et al, 2016). (Moghadam et al, 2017) used hexanoic acid to extract Ag (I) and Co (II) from cow milk, vitamin B12, orange juice, and tap water achieving high extraction efficiency, short extraction times and low organic solvent use.…”

Section: Introductionmentioning

confidence: 99%

Integrated disperser freezing purification with extraction using fatty acid-based solidification of floating organic-droplet (IDFP-EFA-SFO) for triclosan and methyltriclosan determination in seawater, sediment and seafood

Gao

Wang

Zhang

et al. 2018

Marine Pollution Bulletin

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TitleIntegrated disperser freezing purification with extraction using fatty acid-based solidification of floating organic-droplet (IDFP-EFA-SFO) for triclosan and methyltriclosan determination in seawater, sediment and seafood. Keywords:Triclosan Methyltriclosan Medium-chain fatty acid Disperser freezing purification Fatty acid-based solidification floating organicdroplet Marine environmental samples A B S T R A C TA microextraction method for the determination of triclosan and methyltriclosan in marine environmental samples was developed. The disperser was first serves as a preliminary extractant for analytes, then as a frozen solvent to remove impurities at −20°C, and finally as a disperser agent in the microextraction procedure. With the extractants solidified and float on the surface of the aqueous phase at low temperature, a separation was achieved to avoided use of specialized laboratory instruments. The method was optimized using Plackett-Burman design and central composite design as follows: 146 μL octanoic acid as extractant, 793 μL acetoneas disperser, 3.0 min centrifugation and 1.1 min vortex time. The limits of detection were 0.022-0.060 μg L −1 or μg kg −1 and recoveries were 83.3-103.5% for TCS and MTCS in seawater, sediments and seafood. The method has excellent prospects for sample pre-treatment and trace-level analysis of triclosan and methyltriclosan in marine environmental samples.

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A fully automated effervescence-assisted switchable solvent-based liquid phase microextraction procedure: Liquid chromatographic determination of ofloxacin in human urine samples

Cited by 100 publications

References 32 publications

Tablet‐effervescence‐assisted dissolved carbon flotation for the extraction of four triazole fungicides in water by gas chromatography with mass spectrometry

Tablet‐effervescence‐assisted dissolved carbon flotation for the extraction of four triazole fungicides in water by gas chromatography with mass spectrometry

An effervescence-assisted switchable fatty acid-based microextraction with solidification of floating organic droplet for determination of fluoroquinolones and tetracyclines in seawater, sediment, and seafood

Integrated disperser freezing purification with extraction using fatty acid-based solidification of floating organic-droplet (IDFP-EFA-SFO) for triclosan and methyltriclosan determination in seawater, sediment and seafood

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