A General Introduction to Traditional Chinese Medicine

Jiu-zhang, Men; Guo, Lei

doi:10.1201/b10164

Cited by 5 publications

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“…Traditional Chinese Medicine (TCM) remains one of the oldest healing systems and is believed to have originated around 3,000 years ago (Jiuzhang and Lei, 2009). Chinese Materia Medica ( Ben Cao ) refers to the botanical, mineral and zoological substances used in TCM, and its oldest record ( Wu Shi Er Bing Fang ) dates back to approximately 1100 BCE and includes 247 natural agents and roughly 150 combinatorial drug formulae (Wu, 2005).…”

Section: Introductionmentioning

confidence: 99%

Validation of a 16th Century Traditional Chinese Medicine Use of Ginkgo biloba as a Topical Antimicrobial

et al. 2019

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In the search for new therapeutic solutions to address an increasing number of multidrug-resistant bacterial pathogens, secondary metabolites from plants have proven to be a rich source of antimicrobial compounds. Ginkgo biloba , a tree native to China, has been spread around the world as an ornamental tree. Its seeds have been used as snacks and medical materials in Traditional Chinese Medicine (TCM), while over the last century its leaf extracts emerged as a source of rising pharmaceutical commerce related to brain health in Western medicine. Besides studies on the neuro-protective effects of Ginkgo, its antibacterial activities have gained more attention from researchers in the past decades, though its leaves were the main focus. We reviewed a 16th-century Chinese text, the Ben Cao Gang Mu by Li Shi-Zhen, to investigate the ancient prescription of Ginkgo seeds for skin infections. We performed antibacterial assays on various Ginkgo seed extracts against pathogens ( Staphylococcus aureus , Cutibacterium acnes , Klebsiella pneumoniae , Acinetobacter baumannii, Streptococcus pyogenes ) relevant to skin and soft tissue infections (SSTIs). We demonstrate here that Ginkgo seed coats and immature seeds exhibit antibacterial activity against Gram-positive skin pathogens ( C. acnes, S. aureus , and S. pyogenes ), and thus validated its use in TCM. We also identified one compound tied to the antibacterial activity observed, ginkgolic acid C15:1, and examine its toxicity to human keratinocytes. These results highlight the relevance of ancient medical texts as leads for the discovery of natural products with antimicrobial activities.

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Section: Introductionmentioning

confidence: 99%

Validation of a 16th Century Traditional Chinese Medicine Use of Ginkgo biloba as a Topical Antimicrobial

et al. 2019

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2023

The Greening of Pharmaceutical Engineering Volume 4

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An ethnobotanical study of medicinal plants in Sheka Zone of Southern Nations Nationalities and Peoples Regional State, Ethiopia

Kassa

Asfaw

Demissew

2020

J Ethnobiology Ethnomedicine

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Background: People's classification, management, and use of plants represent attempt to attracting people from different academic disciplines. Many countries use traditional medicine for their primary healthcare system. Medicinal plants have been important components of healthcare systems since the time immemorial. The objective of this research was to document and analyze traditional medicinal plants used by the Sheka people and associated ethnobotanical knowledge. Methods: Data was collected by administering pre-prepared semi-structured interview items to 414 informants. Market surveys, group discussion, and guided field walk were used. Data were analyzed using descriptive and inferential statistics; determination of informant consensus factor, fidelity level, as well as ranking and scoring. Results: A total of 266 plant species belonging to 192 genera and 74 families were identified. About 204 (77%) of the medicinal plants were used to treat human health problems. Only ten (4%) were used to treat livestock health problems and 52 (19%) of them were used to treat both human and livestock health problems. Croton macrostachyus, Prunus africana, Peperomia retusa, Lobelia giberroa, and Celosia schweinfurthiana were found to be high ranking medicinal plants against gastrointestinal problems based on simple preference ranking. Conclusion: Very high number of medicinal plant species recorded from the study area indicates that vegetation of Sheka is reservoir of medicinal plants. Hence, the area needs attention for medicinal plant conservation priorities. Plant parts used as medicines also play vital role in the entire medicinal plant life cycle. Therefore, it is useful to consider harvesting impacts. Except well-experienced traditional healers, people of the study area use the medicinal plants haphazardly. There may be high risk of being victims of dosage and improper usage. High ranking medicinal plants are candidates for further phytochemical profiling, drug research, and development.

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A General Introduction to Traditional Chinese Medicine

Cited by 5 publications

References 0 publications

Validation of a 16th Century Traditional Chinese Medicine Use of Ginkgo biloba as a Topical Antimicrobial

Validation of a 16th Century Traditional Chinese Medicine Use of Ginkgo biloba as a Topical Antimicrobial

References and Bibliography

An ethnobotanical study of medicinal plants in Sheka Zone of Southern Nations Nationalities and Peoples Regional State, Ethiopia

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