A Glimpse into Humoral Response and Related Therapeutic Approaches of Takayasu’s Arteritis
Shuning Guo,
Yixiao Tian,
Jing Li
et al.
Abstract:Takayasu’s arteritis (TAK) manifests as an insidiously progressive and debilitating form of granulomatous inflammation including the aorta and its major branches. The precise etiology of TAK remains elusive, with current understanding suggesting an autoimmune origin primarily driven by T cells. Notably, a growing body of evidence bears testimony to the widespread effects of B cells on disease pathogenesis and progression. Distinct alterations in peripheral B cell subsets have been described in individuals with… Show more
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