A green approach for synthesis of naphthoquinone-fused oxazine derivatives in water under ultrasonic irradiation

Cao, Ya-Qian; Li, Xinran; Wu, Wei; Zhang, Dan; Zhang, Zhan‐Hui; Mo, Li‐Ping

doi:10.1007/s11164-016-2854-7

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Cited by 8 publications

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Catalyst Free Synthesis of Bis(Indolyl)Methanes and 3,3‐Bis(Indolyl)oxindoles in Aqueous Ethyl Lactate

2017

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A highly efficient and environmentally friendly approach has been reported for the synthesis of bis(indolyl)methanes and 3,3‐bis(indolyl)oxindoles by reacting of indoles with aldehydes or isatins in water‐ethyl lactate under ultrasound irradiation. This protocol presents the benefits of catalyst‐free, operational simplicity, short reaction time, high product yield, broad substrate scope and applicability for large‐scale synthesis.

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