A green approach for the multicomponent synthesis of polyhydroquinolines and 6-unsubstituted dihydropyrimidinones using novel highly proficient acidic ionic liquid [CEMIM][MSA] as a reusable catalyst

The Synthesis of Nitrogen- and Oxygen-Containing Heterocyclic Scaffolds Assisted by Ionic Liquids: A 2022 Literature Survey

“…Next, they used it for the synthesis of polyhydroquinolines 101 starting from dimedone (4), ethyl acetoacetate (100), NH 4 OAc (8) and aldehydes 1 (Scheme 31). 91 The effects of various solvents and reaction conditions were investigated, leading to excellent yields of products 101 at 75 °C in an aqueous medium. Activation of the aryl aldehyde by the imidazolium cation moiety promotes the Knoevenagel condensation.…”

Exploring Untouched Variant of Bis(2‐methyl‐1H‐indol‐3‐yl)methane: Enhances Chemo and Mono‐Selectivity

“…[3] You can directly obtain indoles with various carbonyl functional groups by using both homo-and heterogeneous catalysts. These catalysts cover a broad spectrum, encompassing acid catalysts, [4][5][6][7][8][9][10][11][12][13][14] Nano catalysts, [15][16][17][18][19][20][21] supported catalysts, [22][23][24][25][26][27][28][29][30][31][32][33][34][35] metal catalysts, [36][37][38][39][40][41][42][43] ion exchange resin, [44] and enzymes. [45] Reactions catalyzed by acids in this context involve substances such as HCl, [46] P 2 O 5 , [47] Amberlyst-15, [48] and solidified acids.…”

Isomerization of C7 and C8 through Ionic Liquids Supported by a Fe/SBA-15 Catalyst

“…Some dominant features are that they have low vapor pressure, a low melting point, and low volatilities and are nonflammable in nature. Then, the fact that the chemical and physical properties of the ILs depend on different cationic and anionic constituents increase interest in them. − Besides these features, it also has some drawbacks, such as having an unbearable viscosity, which will restrict its widespread applications. Immobilized ILs have taken on a dominant role with numerous advantages immobilization mainly lowers the consumption of ILs, increases recyclability, simplifies the purification methods of products with less contamination, and is used in gaseous reactions. − ILs tend to show excellent thermal stability and are notably nonvolatile and nonflammable, but they are able to ignite when high-energy moieties such as tetrazoles or nitro groups are present or when temperatures approach their decomposition temperature. , ILs containing phosphonium exhibit intermediate base stability.…”