A heating-assisted liquid-liquid microextraction approach using menthol: Separation of benzoic acid in juice samples followed by HPLC-UV determination

Fabric phase sorptive extraction-gas chromatography-mass spectrometry for the determination of favipiravir in biological and forensic samples

“…This is the first ever application of GC-MS analysis for determining FAV. The proposed FPSE-GC-MS approach has achieved lower LODs and LOQs than previously reported methods [ 38 , [39] , [40] , [41] , [42] ]. This could be due to the low enrichment of sample preparation procedures (LLE & SPE) used in these approaches for the extraction of FAV.…”

Menthol-assisted homogenous liquid-liquid microextraction for HPLC/UV determination of favipiravir as an antiviral for COVID-19 in human plasma

“…In addition, menthol is used as a co-acervating agent in the menthol/water/decyl amine system [33] . Recently, menthol has been used as a liquid extractant after being melted for extraction of benzoic acid from berry juice [34] . The amount of menthol is critical in menthol-assisted HLLME.…”

“… SWV 4.5–8640 ≤1.53 4.5 [37] Human plasma Liquid-liquid extraction by dichloromethane using 1000 µL of plasma. HPLC/UV 3000–60000 3.04 3000 [34] Human plasma Menthol-assisted HLLME using 1500 µL of plasma. HPLC/UV 100–100000 8.15 100 This work SWV: Square Wave Voltammetry; SW-AdSV: Square-wave adsorptive stripping voltammetry.…”

Cyclodextrin-assisted dispersive liquid-liquid microextraction based on solidification of floating organic droplets coupled with HPLC for the determination of pyrethroid residues in cereals

“…However, the traditional extraction solvents such as carbon tetrachloride, chloroform, and chlorobenzene are highly toxic. Green and cheap solvent should be used as the extraction solvent in DLLME methods [15]. Ionic liquids and deep eutectic solvents have been considered as green alternatives to conventional solvents for organic contaminants extraction [16,17].…”