A hemispherotomy for intractable startle epilepsy characterized by infantile hemiplegia and drop attacks

Postherpetic Anti-N-methyl-D-aspartate Receptor Encephalitis after Hemispherotomy in a Patient with Intractable Startle Epilepsy

“…Unfortunately, there is not enough data on this treatment paradigm, and only two cases have been published in the literature. 7,8 Our patient is the third case with intractable startle-induced seizures and a unilateral large hemispheric lesion who was seizure-free 1 year after hemispherotomy despite serious complications.…”

“…There are only two published cases of hemispherotomy as a treatment option for startle-induced seizures and large hemispheric lesions. 7,8 Here, we present an original case with postherpetic anti-NMDAR encephalitis after hemispherotomy for intractable startle epilepsy.…”

Endoscopy-Assisted Interhemispheric Transcallosal Hemispherotomy

“…Hemispherotomy can achieve excellent outcomes when performed in optimally indicated patients. 3,[6][7][8]10,14,16,18,20,28,35,[43][44][45][46][47][48][49][50][51][52][53] Since the introduction of functional hemispherectomy by Rasmussen, morbidity and mortality have steadily decreased. 8,10,11,13,14,28,[43][44][45][46][47]54 However, this procedure still cannot be considered as a trivial surgery because most of the surgeries are performed in children who cannot tolerate blood loss and are prone to other perioperative morbidities such as hypothermia, electrolyte disturbances, and other problems associated with pediatric patients.…”

Surgical treatment in startle epilepsy

“…[1] Most patients are sensitive to auditory or somatosensory stimuli. Most patients with startle epilepsy have structural brain lesions, the common ones being birth-related injury.…”

“…Recently, surgical treatment in medically refractory startle epilepsy has been reported. [1,2] We report a patient with medically refractory startle epilepsy who underwent a surgical treatment with seizure remission (Engle Class I).…”