2024
DOI: 10.1038/s41467-024-54257-3
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A hierarchical active inference model of spatial alternation tasks and the hippocampal-prefrontal circuit

Toon Van de Maele,
Bart Dhoedt,
Tim Verbelen
et al.

Abstract: Cognitive problem-solving benefits from cognitive maps aiding navigation and planning. Physical space navigation involves hippocampal (HC) allocentric codes, while abstract task space engages medial prefrontal cortex (mPFC) taskspecific codes. Previous studies show that challenging tasks, like spatial alternation, require integrating these two types of maps. The disruption of the HC-mPFC circuit impairs performance. We propose a hierarchical active inference model clarifying how this circuit solves spatial int… Show more

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