Abstract:High fat diets can attenuate cardiac hypertrophy in Dahl Salt Sensitive rats (DSS), a model of severe hypertension, cardiac hypertrophy & dysfunction, independent of changes in blood pressure. We hypothesized that a high fat diet can prevent hypertrophy in spontaneously hypertensive rats (SHR), a model of gradually increasing hypertension. Five‐week old SHR and Wistar Kyoto (WKY; normotensive control) rats were fed either a low fat (LF) or high fat (HF) diet with 10% and 60% of Calories from lard, respecti… Show more
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