A highly selective “turn-on” fluorescent chemosensor based on 8-aminoquinoline for detection of Zn<sup>2+</sup>

Yue, Yuanyuan; Dong, Qiaoxiang; Zhang, Yajie; Sun, Yangyang; Gong, Yan

doi:10.1039/c5ay01007a

Cited by 36 publications

(18 citation statements)

References 33 publications

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“…In determining the binding studies between receptor 8-amidoquinoline compounds, all the papers reviewed were reported on characterization spectroscopy, fluorescence titration, and UV-Vis titration [42,112,118]. They seek binding mode via job plot method and binding constant (K d ) or association constant (K a ).…”

Section: Binding Studies Of 8-amidoquinoline Probes Via Solution Studiesmentioning

confidence: 99%

The Role of 8-Amidoquinoline Derivatives as Fluorescent Probes for Zinc Ion Determination

Mohamad

Zakaria

Daud

et al. 2021

Sensors

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Mass-spectrometry-based and X-ray fluorescence-based techniques have allowed the study of the distribution of Zn2+ ions at extracellular and intracellular levels over the past few years. However, there are some issues during purification steps, sample preparation, suitability for quantification, and the instruments’ availability. Therefore, work on fluorescent sensors based on 8-aminoquinoline as tools to detect Zn2+ ions in environmental and biological applications has been popular. Introducing various carboxamide groups into an 8-aminoquinoline molecule to create 8-amidoquinoline derivatives to improve water solubility and cell membrane permeability is also a recent trend. This review aims to present a general overview of the fluorophore 8-aminoquinoline and its derivatives as Zn2+ receptors for zinc sensor probes. Various fluorescent chemosensor designs based on 8-amidoquinoline and their effectiveness and potential as a recognition probe for zinc analysis were discussed. Based on this review, it can be concluded that derivatives of 8-amidoquinoline have vast potential as functional receptors for zinc ions primarily because of their fast reactivity, good selectivity, and bio-compatibility, especially for biological applications. To better understand the Zn2+ ion fluorophores’ function, diversity of the coordination complex and geometries need further studies. This review provides information in elucidating, designing, and exploring new 8-amidoquinoline derivatives for future studies for the improvement of chemosensors that are selective and sensitive to Zn2+.

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Section: Binding Studies Of 8-amidoquinoline Probes Via Solution Studiesmentioning

confidence: 99%

The Role of 8-Amidoquinoline Derivatives as Fluorescent Probes for Zinc Ion Determination

Mohamad

Zakaria

Daud

et al. 2021

Sensors

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“…Excellent sensitivity and selectivity with 'turn-on' fluorescent probe 46 ( Figure 44) has been detected for Zn 2 + ions. [74] The absorption spectrum of probe 46 displayed an absorption maximum at 239 nm with two broad absorption peaks at (Figure 45) which exhibited a weak fluorescence peak at the wavelength of 386 nm when excited at λ ex = 296 nm owing to PET effect. [75] Upon the introduction of Zn 2 + ions, the fluorescence intensity of 47 has been increased by 3.5-fold, with the emission peak shifted from the region of 386 to 422 nm.…”

Section: P E R S O N a L A C C O U N T T H E C H E M I C A L R E C O R Dmentioning

confidence: 99%

8‐Hydroxyquinoline Fluorophore for Sensing of Metal Ions and Anions

Rohini

Paul

Luxami

2020

The Chemical Record

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Among various known hydroxyquinolines, 8-hydroxyquinoline (8-HQ) is the most prevalent moiety due to excellent property for the formation of the complex with different metal ions and anions, and utilized in a wide variety of applications in pharmacological and medicinal fields. 8-Hydroxyquinoline moiety and its analogues acts as fluorophoric ligands on complex formation with alkali and alkaline as well as transition metal ions and anions, thus, considered as an ideal building block in metallo-supramolecular chemistry for recognition, separation, and quantitative investigation of cations. 8-Hydroxyquinoline moiety is also used in various applications for the advancement of novel fluorescent chemosensors in a wide variety of areas viz., material chemistry, bioorganic chemistry, molecular imaging, analytical chemistry, molecular recognition, medical and biological science communities. The present review emphasises on the progress of sensing properties of 8-HQ centred small-molecule fluorescent chemosensors towards several metal ions viz.

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“…In determining the binding studies between receptor 8-amidoquinoline compounds, all the papers reviewed were reported on characterization spectroscopy, fluorescence titration, and UV-Vis titration [20,43,73]. They seek for binding mode via job plot method and binding constant (Kd) or association constant (Ka).…”

Section: Binding Studies Of 8-amidoquinoline Probes Via Solution Workmentioning

confidence: 99%

“…The only difference in those studies is the interference metals, and the metal ratio to zinc used. Nevertheless, certain studies [20,47,50,58,60,64,65,67] demonstrated that the sensing probe could be used in a real sample due to the metals involved not present or least in biological applications. These exhibited 8-amidoquinoline derivatives are selective to zinc detection due to minor interferences issues.…”

Section: Interferences Of Other Competitive Metal Cationsmentioning

confidence: 99%

“…As ion-induced sensors, a fluorescent probe is highly useful for various applications such as in vivo and in vitro analyses of biologically essential species, including metal ions. It offers many advantages over other techniques because of its high sensitivity, selectivity, instantaneous response besides offering instrument less detection [20]. Despite the progress of fluorescent chemosensors in various detection, several problems and challenges continue to have existed lead to an exploration of the development of binding receptors.…”

Section: Introductionmentioning

confidence: 99%

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Investigating the Potential of 8-Amidoquinoline Derivatives as a Fluorescent Probe for Zinc Detection: A Systematic Literature Review

Hassan¹,

Mohamad²,

Zakaria³

et al. 2020

Preprint

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Abundant of preparatory works have recognized that fluorescent sensors based on 8-aminoquinoline are popular tools to detect Zn2+ ions in environmental and biological applications. Along with these studies, researchers started to introduce a variety of carboxamido group into an 8-aminoquinoline molecule in forming 8-amidoquinoline derivatives. Therefore, this systematic review aims to introduce a general overview of the fluorophore 8-aminoquinoline as Zn2+ receptors and to provide comparisons of collected studies that related to 8-amidoquinoline derivatives as fluorophore probe of the sensor. According to PRISMA systematic searches strategy, 13 articles were analyzed for trends, research designs, results and discussion, subject samples, and remarks or conclusions. We found cross-sectional studies with four aspects in zinc sensing that have been targeted; binding studies via titration, detection's limit, interferences studies, and validation of the study. Hence, this paper also included assessments of those criteria and the trends of development of 8-amidoquinoline derivatives based-zinc fluorescent chemosensor. It also showed that most of the researches conducted in China. In conclusion, this study identified various research designs of fluorescent chemosensors based on 8-amidoquinoline prolong with the effectiveness and potential as a recognition probe to assist the detection of zinc. Hence, elucidation of those derivatives essential to be explored because more studies are needed to improve the sensing criteria of the zinc sensor

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A highly selective “turn-on” fluorescent chemosensor based on 8-aminoquinoline for detection of Zn²⁺

Cited by 36 publications

References 33 publications

The Role of 8-Amidoquinoline Derivatives as Fluorescent Probes for Zinc Ion Determination

The Role of 8-Amidoquinoline Derivatives as Fluorescent Probes for Zinc Ion Determination

8‐Hydroxyquinoline Fluorophore for Sensing of Metal Ions and Anions

Investigating the Potential of 8-Amidoquinoline Derivatives as a Fluorescent Probe for Zinc Detection: A Systematic Literature Review

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A highly selective “turn-on” fluorescent chemosensor based on 8-aminoquinoline for detection of Zn2+

Cited by 36 publications

References 33 publications

The Role of 8-Amidoquinoline Derivatives as Fluorescent Probes for Zinc Ion Determination

The Role of 8-Amidoquinoline Derivatives as Fluorescent Probes for Zinc Ion Determination

8‐Hydroxyquinoline Fluorophore for Sensing of Metal Ions and Anions

Investigating the Potential of 8-Amidoquinoline Derivatives as a Fluorescent Probe for Zinc Detection: A Systematic Literature Review

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A highly selective “turn-on” fluorescent chemosensor based on 8-aminoquinoline for detection of Zn²⁺