A highly sensitive electrochemiluminescence method combined with molecularly imprinted solid phase extraction for the determination of phenolphthalein in drug, slimming food and human plasma

Guo, Zhiyong; Hao, Tingting; Shi, Lili; Gai, Panpan; Duan, Jing; Wang, Sui; Gan, Ning

doi:10.1016/j.foodchem.2011.11.056

Cited by 24 publications

(3 citation statements)

References 29 publications

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“…20 Cui et al 21 dopamine, 32 and phenolphthalein. 33 Most analytes involved in the quenched ECL are limited to some specific compounds, i.e. phenols and their derivatives.…”

Section: +mentioning

confidence: 99%

Determination of Brilliant Blue FCF by a Novel Solid-state ECL Quenching Sensor of Ru(bpy)32+-poly(sulfosalicylic acid)/GCE

et al. 2017

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“…20 Cui et al 21 dopamine, 32 and phenolphthalein. 33 Most analytes involved in the quenched ECL are limited to some specific compounds, i.e. phenols and their derivatives.…”

Section: +mentioning

confidence: 99%

Determination of Brilliant Blue FCF by a Novel Solid-state ECL Quenching Sensor of Ru(bpy)32+-poly(sulfosalicylic acid)/GCE

et al. 2017

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“…Compared with classical SPE methods, MISPE provides high selectivity and allows analytes to be eluted from cartridges almost free of co-extracted compounds. 21 The potential value of MISPE lies in its ability to selectively isolate specific compounds or their structural analogs from a complex matrix. The use of these synthetic polymers as sorbents allows the analytes of interest to be preconcentrated while simultaneously removing interfering compounds from the matrix so that selective enrichment and cleanup are obtained, resulting in a higher accuracy and a lower detection limit in the subsequent analysis.…”

Section: Introductionmentioning

confidence: 99%

Preparation and application of acrylamide molecularly imprinted composite solid-phase extraction materials

2012

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A novel acrylamide (AA) molecularly imprinted material based on silica microparticles was synthesized successfully by a surface polymerization method using propionamide (PAM) as a template molecule, methacrylic acid (MAA) as a functional monomer, and ethylene glycol dimethacrylate (EGDMA) as a cross-linker. The molecularly imprinted polymers (MIP) on the surfaces of silica microparticles were characterized using infrared spectroscopy and scanning electron microscopy, and the results suggested that the MIP was successfully grafted onto the silica surface. The amount of AA adsorbed on the MIP was measured using high-performance liquid chromatography (HPLC) and equilibrium binding experiments. The results of static adsorption equilibrium experiments and Scatchard analysis showed that compared with non-imprinted polymers, the imprinted polymer had a significantly higher adsorption capacity for AA. Scatchard analysis revealed that two classes of binding sites were formed in the MIP with dissociation constants of 0.182 and 0.099 mmol mL À1 , and the maximum apparent binding capacities were 16.18 and 54.18 mmol g À1 . The new adsorbent was successfully used in solidphase extraction (SPE) to selectively enrich and determine AA in fried food samples. The experimental results indicated that the MIP-SPE column gave recoveries higher than 93% with a relative standard deviation (RSD) of less than 2.24%, much better than those obtained using a commercial C18-SPE column, which gave a recovery of less than 24% with RSD < 2.07%. The developed MIP-SPE/HPLC protocol improved the selectivity and eliminated the effects of template leakage on quantitative analysis, and could be used for the determination of AA in complex food samples.

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“…The synthetic program is based on the copolymerization of functional monomers and cross-linkers to form complexes with the template molecules, after the removal of the template, the special tailor-made binding sites that are complementary in size shape and functionality to template are obtained 3 . Due to the desired predetermination, high specific selectivity and practicability, MIPs have been widely used in various significant applications, such as chemical sensor 4 , solid phase extraction 5 , artificial antibodies 6 , stationary phases in chromatography 7 , extraction and separation 8 9 , catalysis 10 11 12 , drug delivery and controlled release 13 14 15 and so on. However, the bulk MIPs exhibit high selective recognition but have low binding kinetics, poor binding capacity, and shortcomings of incomplete template, attributing to the high difficult of the extraction of template molecules embedded inside the thick polymer network 16 .…”

mentioning

confidence: 99%

A Novel Sensitive Luminescence Probe Microspheres for Rapid and Efficient Detection of τ-Fluvalinate in Taihu Lake

Wang

Qiu

et al. 2017

Sci Rep

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Fluorescent molecularly imprinted polymers have shown great promise in biological or chemical separations and detection, due to their high stability, selectivity and sensitivity. In this work, fluorescent molecularly imprinted microsphere was synthesized via precipitation polymerization, which could separate efficiently and rapidly detect τ-fluvalinate (a toxic insecticide) in water samples, was reported. The fluorescent imprinted sensor showed excellent stability, outstanding selectivity and the limit of detection low to 12.14 nM, good regeneration ability which still kept good sensitivity after 8 cycling experiments and fluorescence quenching mechanism was illustrated in details. In addition, the fluorescent sensor was further used to detect τ-fluvalinate in real samples from Taihu Lake. Despite the relatively complex components of the environment water, the fluorescent imprinted microspheres sitll showed good recovery, clearly demonstrating the potental value of this smart sensor nanomaterial in environment monitoring.

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A highly sensitive electrochemiluminescence method combined with molecularly imprinted solid phase extraction for the determination of phenolphthalein in drug, slimming food and human plasma

Cited by 24 publications

References 29 publications

Determination of Brilliant Blue FCF by a Novel Solid-state ECL Quenching Sensor of Ru(bpy)32+-poly(sulfosalicylic acid)/GCE

Determination of Brilliant Blue FCF by a Novel Solid-state ECL Quenching Sensor of Ru(bpy)32+-poly(sulfosalicylic acid)/GCE

Preparation and application of acrylamide molecularly imprinted composite solid-phase extraction materials

A Novel Sensitive Luminescence Probe Microspheres for Rapid and Efficient Detection of τ-Fluvalinate in Taihu Lake

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