1986
DOI: 10.1097/00006254-198601000-00008
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A Histopathologic Evaluation of Nevocellular Nevi in Pregnancy

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Cited by 23 publications
(37 citation statements)
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“…Hormones may play a role in the pattern of nevi in Turner syndrome. It is known that acquired nevomelanocytic nevi may enlarge during puberty (38) and may increase in number and size, as well as become darker during pregnancy (39). The fact that patients with Turner syndrome have elevated levels of luteinizing hormone and follicle-stimulating hormone during infancy, as well as higher levels at age 10 and 11 years compared with normal girls (40), raises interesting questions about the possible role of hormones in the development and transformation of nevi.…”
Section: Discussionmentioning
confidence: 99%
“…Hormones may play a role in the pattern of nevi in Turner syndrome. It is known that acquired nevomelanocytic nevi may enlarge during puberty (38) and may increase in number and size, as well as become darker during pregnancy (39). The fact that patients with Turner syndrome have elevated levels of luteinizing hormone and follicle-stimulating hormone during infancy, as well as higher levels at age 10 and 11 years compared with normal girls (40), raises interesting questions about the possible role of hormones in the development and transformation of nevi.…”
Section: Discussionmentioning
confidence: 99%
“…Although the impact of age was not specifically addressed in this study, our experience is these changes are much more prevalent in young adults than in the elderly. The role estrogen plays in the biology and altered histology of breast lesions is intriguing 29,30 but yet unfounded. These features are found on breast lesions of both men and women and are not restricted to the papillomatous variety of pregnancy, 31 for now arguing against the sole impact of the hormonal milieu.…”
Section: Breastmentioning
confidence: 99%
“…In general, histologic comparison of nevus samples from pregnant women to non-pregnant controls have failed to note a significant difference in cytologic atypia between the study and the control groups (4,(6)(7)(8). However, one series did report a trend towards increased histopathological atypia in nevi from pregnant patients (8). A photographical, clinical and histological analysis of patients with the dysplastic nevus syndrome (DNS) (9) used clinical photographs and histopathology to document both a macroscopic increase in nevi changes and histopathological dysplasia during pregnancy.…”
Section: Introductionmentioning
confidence: 98%
“…However, many of these reports have been criticized because of their reliance on subjective reports from patients regarding nevus size and colour changes (6). In general, histologic comparison of nevus samples from pregnant women to non-pregnant controls have failed to note a significant difference in cytologic atypia between the study and the control groups (4,(6)(7)(8). However, one series did report a trend towards increased histopathological atypia in nevi from pregnant patients (8).…”
Section: Introductionmentioning
confidence: 99%