A Janus adhesive hydrogel sheet for preventing postoperative tissue adhesion of intestinal injuries

Li, Jingmei; Liang, Jiadi; Chen, Shanshan; Guo, Wucheng; Chen, Ting; Liu, Xiqiang

doi:10.1039/d3ra08867g

Cited by 2 publications

(1 citation statement)

References 35 publications

(56 reference statements)

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“…In addition to strong adhesion, preventing postoperative adhesion is also crucial in the treatment of intestinal perforation. 33–35 Based on the thermal reversible injectability of GTPC, the GTPC hydrogel was injected in the sol state when it was used in vivo , during which the hydrogen bond interaction between gelatin and catechol was partially destroyed. When the GTPC sol was in contact with the tissue, the catechol group could achieve effective in situ adhesion through multiple interactions with the tissue.…”

Section: Resultsmentioning

confidence: 99%

A thermally reversible injectable adhesive for intestinal tissue repair and anti-postoperative adhesion

Zhang,

Yang

et al. 2024

Biomater. Sci.

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Section: Resultsmentioning

confidence: 99%

A thermally reversible injectable adhesive for intestinal tissue repair and anti-postoperative adhesion

Zhang,

Yang

et al. 2024

Biomater. Sci.

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Advances in Adhesive Materials for Oral and Maxillofacial Soft Tissue Diseases

Cheng,

Xu,

Luo

et al. 2024

Macromolecular Bioscience

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Oral diseases represent a prevalent global health burden, profoundly affecting patients' quality of life. Given the involvement of oral mucosa and muscles in diverse physiological functions, coupled with clinical aesthetics considerations, repairing oral and maxillofacial soft tissue defects poses a formidable challenge. Wet‐adhesive materials are regarded as promising oral repair materials due to their unique advantages in easily overcoming physical and biological barriers in the oral cavity. This review first introduces the intricate wet‐state environment prevalent in the oral cavity, meticulously explaining the fundamental physical and chemical adhesion mechanisms that underpin adhesive materials. It then comprehensively summarizes the diverse types of adhesives utilized in stomatology, encompassing polysaccharide, protein, and synthetic polymer adhesive materials. The review further evaluates the latest research advancements in utilizing these materials to treat various oral and maxillofacial soft tissue diseases, including oral mucosal diseases, periodontitis, peri‐implantitis, oral and maxillofacial skin defects, and maxillofacial tumors. Finally, it also highlights the promising future prospects and pivotal challenges related to stomatology application of multifunctional adhesive materials.

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A Janus adhesive hydrogel sheet for preventing postoperative tissue adhesion of intestinal injuries

Abstract: A Janus hydrogel sheet with a unique combination of tissue adhesion and biological inertness was prepared in the study.

Cited by 2 publications

References 35 publications

A thermally reversible injectable adhesive for intestinal tissue repair and anti-postoperative adhesion

A thermally reversible injectable adhesive for intestinal tissue repair and anti-postoperative adhesion

Advances in Adhesive Materials for Oral and Maxillofacial Soft Tissue Diseases

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