A label-free immunosensor based on recordable compact disk chip for early diagnostic of the dengue virus infection

Apropos “A label-free immunosensor based on recordable compact disk chip for early diagnostic of the dengue virus infection”

“…We compliment the team of investigators from Brazil [1] for their standardization of a label-free immunosensor that exhibited a good reliability for Dengue virus NS1 antigen detection during the early phase of dengue virus infection. Nevertheless, for the maximum utility of any label-free immunosensor in resource-poor countries, it would be desirable to update the immunosensor techniques towards a simultaneous detection of Dengue virus NS1, IgM and IgG antibody and also to enumerate circulating platelets in the blood.…”

The role of nanogold in human tropical diseases: research, detection and therapy

“…As Foguel et al [29] suggested for T. Cruzi detection, Cavalcanti et al [82] also used a gold film electrode obtained from a recordable compact disk, but for the detection of non-structural protein 1 (NS1) of the dengue virus. This protein is abundantly present in blood during the acute phase of the dengue infection, in a correlation with viremia levels and, consequently, can be used to early diagnostic of the dengue hemorrhagic fever.…”

Nanoscale virus biosensors: state of the art

“…An electrochemical immunosensor based on goldfilm electrode, obtained from a recordable compact disk (CD-electrode), was developed by Cavalcanti et al 125 for nonstructural protein 1 (NS1) of DV detection. Anti-NS1 monoclonal antibodies were immobilized on the CDelectrode via protein A.…”

“…Anti-NS1 monoclonal antibodies were immobilized on the CDelectrode via protein A. 125 The NS1 interaction with anti-NS1 immobilized on CD-electrode was detected by DPV. 125 The immunosensor showed the detection limit of 0.33 ng mL 86 Amperometric responses to the NS1 of DV were obtained by CV in the presence of ferrocyanide/ferricyanide as redox probe.…”

“…125 The NS1 interaction with anti-NS1 immobilized on CD-electrode was detected by DPV. 125 The immunosensor showed the detection limit of 0.33 ng mL 86 Amperometric responses to the NS1 of DV were obtained by CV in the presence of ferrocyanide/ferricyanide as redox probe. 86 Xie et al 126 reported EB for AIV H5 subtype detection using graphene oxide-H5-polyclonal antibodies-bovine serum albumin (GO-PAb-BSA) nanocomposite.…”