A Laboratory Facility for the Controlled Exposure of Blood Vessels to High-Intensity Focused Ultrasound

Беркович, А. Е.; Bursian, A. A.; Senchik, K U; Петрищев, Н. Н.; Tsibin, A U; Yukina, G U

doi:10.1007/s10527-016-9596-0

Cited by 5 publications

(4 citation statements)

References 4 publications

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“…During the last two decades this method is being developed in a number of scientific centers [7][8][9]. Animal studies are carried out for approbation of the method [10][11][12][13]. The sensitivity of the method is evaluated on test objects with known temperature fields [14][15].…”

Section: Objectivesmentioning

confidence: 99%

On accuracy estimation of ultrasonic thermometry technique with heated wire method

et al. 2018

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Section: Objectivesmentioning

confidence: 99%

On accuracy estimation of ultrasonic thermometry technique with heated wire method

et al. 2018

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“…Previous animal studies demonstrated structural alterations of the whole vascular wall after HIFU treatment ( 10 , 11 ). Following a session of HIFU treatment, endothelial desquamation, subendothelial edema, and leukocyte infiltration were detected in the vascular intima ( 10 ). Histological examination of the vascular media and adventitia revealed collagen shrinkage, separation, and disruption ( 10 ).…”

Section: Discussionmentioning

confidence: 93%

“…Following a session of HIFU treatment, endothelial desquamation, subendothelial edema, and leukocyte infiltration were detected in the vascular intima ( 10 ). Histological examination of the vascular media and adventitia revealed collagen shrinkage, separation, and disruption ( 10 ). The thermal coagulation effect caused by tissue absorption of HIFU mediates hyalinization and stiffening of the collagen fiber in the vascular media, making the vessel fragile and prone to rupture ( 12 ).…”

Section: Discussionmentioning

confidence: 99%

Case report: Traumatic carotid artery dissection after 7D High-Intensity Macro- and Micro-Focused Ultrasound treatment for skin laxity of the neck

Shao

Lai

et al. 2022

Front. Cardiovasc. Med.

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BackgroundTrauma is a relatively uncommon etiology of carotid artery dissection. Trauma is both penetrative and trivial, which can lead to carotid artery dissection. In the current study, we present an unusual case in which carotid artery dissection was potentially triggered by the damaging thermal effect of 7D High-Intensity Macro- and Micro-Focused Ultrasound (7D HIFU), which has been proposed as a safe and effective non-surgical modality for skin rejuvenation.Case summaryA 41-year-old woman developed headache and clinical manifestations of cerebral infarction after 7D HIFU, aimed at removing neckline. Head and neck magnetic resonance angiography (MRA) and computed tomography angiogram (CTA) revealed severe stenosis and dissection of the left internal carotid artery. Neither the patient's history nor the physical examination showed any special indicators. After resection of the left carotid artery dissection, autologous great saphenous vein interposition grafting, and simple mastoidectomy, the patient underwent head and neck MRA, which revealed recanalization of the left internal carotid artery.ConclusionAlthough mild or moderate complications of 7D HIFU, such as erythema, edema, transient dysesthesia, and motor nerve paresis, have been previously reported, a few previous literature studies documented severe complications of the cosmetic procedure. However, many recent studies pointed out the possibility of 7D HIFU damaging adjacent non-target tissues due to inadequate focal depth of HIFU treatment. Our case is the first to indicate that 7D HIFU could cause carotid artery dissection. We propose that better visualization systems and more rigorous operator training are needed to reduce the risk of the potential off-target damaging effect of 7D HIFU by reporting the case in which the damaging heat effect of 7D HIFU precipitated the carotid artery dissection HIFU.

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“…At the same time, the most common and well-known technology is the ultrasound ablation of soft tissues [5][6][7][8][9][10][11] using HIFU through coagulation necrosis of malignant neoplasms and other soft tissue regions with pathological changes. Strong wave focusing and high radiation intensity in such traditional medical applications are necessary to achieve high temperature (about 80˚-90˚С) in the focal region resulting in thermal ablation of soft tissue.…”

mentioning

confidence: 99%

Spatial Resolution and Measurement Accuracy of the Ultrasound Diagnostic System at Acoustic Remote Palpation Using High Intensity Focusing Ultrasound

Barannik

Pupchenko

Marusenko

et al. 2019

EEJP

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In this work the spatial resolution and measurement accuracy of the ultrasound diagnostic system at acoustic remote palpation (ARP) using high-intensity focusing ultrasound (HIFU) are studied theoretically and experimentally. A physical model is proposed, which describes the specific features of ARP taking into account the remote nature of ultrasound Doppler probing of the soft tissues local movements, which are caused by the radiation pressure of HIFU pulse. Taking into account the accepted simplifying assumptions it is shown that the model conclusions are in a good agreement with the results of the experiments on measuring the value of displacements under the influence of HIFU. In particular, the nontrivial dependence of the value of displacements, measured by the Doppler method, on the probing depth and focusing degree of the incident and scattered wave beams, is proved. An experimental study was performed on the transverse resolution at ARP in the case of probing of the medium with Young's modulus irregularity, as well as on the influence of noise and interference on the measurement accuracy and resolution. It is concluded, that the transverse resolution at ARP is determined by the parameters of the local area of the movement, and can be significantly higher than the transverse intrinsic resolution of the ultrasound system at B-mode of diagnostics. The obtained results indicate that ARP is a promising method for monitoring the process of the soft tissues thermal ablation, when HIFU is used.

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A Laboratory Facility for the Controlled Exposure of Blood Vessels to High-Intensity Focused Ultrasound

Cited by 5 publications

References 4 publications

On accuracy estimation of ultrasonic thermometry technique with heated wire method

On accuracy estimation of ultrasonic thermometry technique with heated wire method

Case report: Traumatic carotid artery dissection after 7D High-Intensity Macro- and Micro-Focused Ultrasound treatment for skin laxity of the neck

Spatial Resolution and Measurement Accuracy of the Ultrasound Diagnostic System at Acoustic Remote Palpation Using High Intensity Focusing Ultrasound

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