A large functional somatostatinoma in the pancreatic tail: Atypical CT appearances

Yu, Ri‐Sheng; Chen, Ying; Wang, Liu-Hong; Xu, Xiufang; Jiang, Dingyao

doi:10.4318/tjg.2009.0030

Cited by 3 publications

(2 citation statements)

References 15 publications

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“…The estimated annual incidence is 1 in 40 million [14] with a median age at onset of 54 years (range 24-84 years). No racial predilection Deschamps et al [27] Colovic et al [28] Yu et al [29] He et al [30] Cao et al [31] Chetty et al [32] South et al [33] Takai et al [34] Nesi et al [35] Sakorafas et al [36] Biffoni et al [37] Sreenarasimhaiah et al [38] Peskova et al [39] Martinez-Penalver Gutierrez et al [40] Bettini et al [41] Choi et al [42] Guercioni et al [43] Morisawa et al [44] Marakis et al [45] Kim et al [46] Hendi et al [47] Bastian et al [48] Fendrich et al [49] Kimura et al [50] Suzuki et al [51] Cappelli et al [52] Ohwada et al [53] Tomono et al [54] Patel et al [55] Takashi et al [56] Wakeman et al [57] Usui et al [6] House et al [58] Gregersen et al [59] Green et al [60] Guo et al [61] Rios et al [19] Borobia et al [62] Karasawa et al [4] Cohen et al [63] Tanaka et al [64] Table 3 Reports of Somatostatinoma published during the last decade mal ...…”

Section: Discussionmentioning

confidence: 99%

Duodenal somatostatinoma

et al. 2010

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Aim -Background: Somatostatinomas is a very rare neuroendocrine tumour of the gastrointestinal tract, first described in the pancreas in 1977 and in the duodenum in 1979. We present the case a 67-year-old woman with duodenal somatostatinoma that was resected with a pancreaduodenectomy procedure and also provide a brief review of the literature. Method: Databases from Pubmed and Medline were searched using a list of keywords such as somatostatinoma, duodenum, pancreas, neuroendocrine tumour and references from review articles.The study of such a case and those in the literature provides useful knowledge into the clinical management and diagnosis of these patients. Results: The search of the literature yielded 348 articles, 92 reviews, 175 case reports, 328 journal articles, 6 clinical trials, 1 editorial, 21 comparative studies and 3 multicenter studies. Forty-five articles related to type-1 neurofibromatosis were found, 5 associated with von Hippel-Lindau disease and 33 associated with multiple endocrine neoplasia type-1. Around 201 cases of somatostatinoma were reported Conclusion: Two different symptomatic presentations can be found that include the inhibitory syndrome in pancreatic somatostatinomas, whereas tumours arising from the duodenal wall are usually associated with mechanical enteric obstructive symptoms. The clinical symptoms are often variable and non-specific; many somatostatinomas are found incidentally during cholecystectomy or during gastrointestinal imaging studies. Surgery is the standard treatment and it is also preferred in metastatic disease providing diagnosis is made early. Patients with metastatic somatostatinoma display 5-year postoperative survival rates of 30-60% as opposed to those without metastasis whose 5-year survival rate approaches 100%.

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Section: Discussionmentioning

confidence: 99%

Duodenal somatostatinoma

et al. 2010

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“…Asymptomatic somatostatinoma accounted for approximately 10% of reported cases 4. The most common locations for tumors were the duodenum and pancreas 5. This tumor was malignant in 60% to 70% of cases with tumor size usually less than 5 cm.…”

Section: Introductionmentioning

confidence: 99%

Gastric Somatostatinoma: An Extremely Rare Cause of Upper Gastrointestinal Bleeding

Prachayakul

Aswakul²,

Deesomsak³

et al. 2013

Clin Endosc

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A 49-year-old woman presented with chronic abdominal discomfort, significant weight loss, and chronic intermittent diarrhea. She suddenly developed massive upper gastrointestinal bleeding and was referred for further treatment. Endoscopy indicated a large mass in the upper gastric body with antral and duodenal bulb involvement. Endosonography showed a large well-defined isoechoic gastric subepithelial mass with multiple intra-abdominal and peripancreatic lymphadenopathy, suspected to be malignant on the basis of fine needle aspiration cytology. The tumor was surgically removed, and histopathology showed typical characteristics of a neuroendocrine tumor. On the basis of immunohistochemical staining, somatostatinoma, a rare neuroendocrine tumor, was diagnosed. Gastrointestinal bleeding is a rare presentation and the stomach is an uncommon tumor location.

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Somatostatinoma

Jones¹,

Weerakkody²

2015

Radiopaedia.org

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A large functional somatostatinoma in the pancreatic tail: Atypical CT appearances

Cited by 3 publications

References 15 publications

Duodenal somatostatinoma

Duodenal somatostatinoma

Gastric Somatostatinoma: An Extremely Rare Cause of Upper Gastrointestinal Bleeding

Somatostatinoma

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