A longitudinal study of long-term quality of life after ileal pouch-anal anastomosis

Results at Up to 30 Years After Ileal Pouch–Anal Anastomosis for Chronic Ulcerative Colitis

“…Because there are no generally accepted QoL measurements after IPAA, most studies use a combination of validated general QoL scores and simple wellbeing questions. 5,11,17,[40][41][42] The majority of patients in this study appeared to enjoy an excellent QoL after IPAA, with good health and good performance scores in all categories, confirming the findings in other studies. 11,17,[40][41][42] Moreover, it has been reported that patients with an IPAA have a better or equivalent QoL than those with a Koch pouch or Brooke ileostomy.…”

“…5,11,17,[40][41][42] The majority of patients in this study appeared to enjoy an excellent QoL after IPAA, with good health and good performance scores in all categories, confirming the findings in other studies. 11,17,[40][41][42] Moreover, it has been reported that patients with an IPAA have a better or equivalent QoL than those with a Koch pouch or Brooke ileostomy. 3,43,44 Although the methods used to determine the impact on QoL in this study has not been validated, the same questions have been asked in the same manner every 5 years for 30 years, so trends toward improvement or deterioration would be expected if significant changes occurred.…”

“…It has since become the restorative procedure of choice for patients with chronic ulcerative colitis (CUC) given its high patient satisfaction, 2,3 good long-term functional outcome, 4 and acceptable morbidity. [5][6][7][8][9][10][11] We previously reported the 20-year results of 1885 CUC patients who underwent IPAA at Mayo Clinic between 1981 and 2000 to better understand the durability of the pouch. 4 In that study, overall pouch success at 5, 10, 15, and 20 years was 96%, 93%, 92%, and 92%, respectively.…”

A Comparison of the Quality of Life of Ulcerative Colitis Patients after IPAA vs Ileostomy

“…Among 5 studies published during the past decade that compared TPC and IPAA subjects, 4 reported that the QOL after IPAA and TPC is the same. [5][6][7][8][9] As such, restoration of normal QOL may be related primarily to the cure of disease-related symptoms, and preservation of the anus may actually have little added effect. 7 In short, it has been remarkably difficult to demonstrate an additional QOL benefit for IPAA after total proctocolectomy in an objective manner.…”

Anal Canal Pressure After Ileal Pouch-Anal Anastomosis with Strengthened Internal Anal Sphincter

“…17 Restoration of quality of life in patients with ulcerative colitis and familial adenomatous polyposis after IPAA represents a serious challenge in modern coloproctology. [18][19][20][21][22][23][24][25] Because this is a relatively small series of consecutive patients, a larger-scale analysis of randomized patients is needed to confirm our preliminary results.…”