A low-cost voltammetric sensor based on multi-walled carbon nanotubes for highly sensitive and accurate determination of nanomolar levels of the anticancer drug Ribociclib in bulk and biological fluids

Abstract

The development and comprehensive characterization of the first electrochemical sensor utilizing multi-walled carbon nanotubes (MWCNTs) for the sensitive and precise detection of Ribociclib (RIBO), an important anticancer drug.

An Ultrasensitive Electrochemical Sensor Using Banana Peel Activated Carbon/NiFe2O4/MnCoFe-LDH Nanocomposites for Anticancer Drug Determination

“…Given that the electron transfer number equates to the number of protons, it can be deduced that the electrochemical oxidation of PLB on the BPAC/NiFe 2 O 4 /MnCoFe-LDH/GCE entails a two-electron and two-proton transfer process. The possible electrochemical oxidation mechanism of PLB has been depicted in Scheme …”

“…According to Laviron's theory, the slope of E p vs ln υ corresponds to RT/ (αnF) for an irreversible electrode reaction process. 36 Consequently, the calculation of the number of protons participating in this electrode reaction process yielded a value of 2.0. Given that the electron transfer number equates to the number of protons, it can be deduced that the electrochemical oxidation of PLB on the BPAC/NiFe 2 O 4 /MnCoFe-LDH/ GCE entails a two-electron and two-proton transfer process.…”