A man with recurrent fever, arthritis, and rashes-brucellosis? A case report

Abstract

Background: We report a rare case of chronic brucellosis accompanied with myelodysplastic syndrome and neutrophilic dermatosis, which to the best of our knowledge, has never been reported. Case presentation: A young man was admitted to our hospital complaining of recurrent fever, arthritis, rashes and anemia. He had been diagnosed with brucellosis 6 years prior and treated with multiple courses of antibiotics. He was diagnosed with myelodysplastic syndrome and neutrophilic dermatosis following bone marrow puncture and skin biopsy. After anti-brucellosis treatment and glucocorticoid therapy, the symptoms improved. Conclusions: Clinicians should consider noninfectious diseases when a patient who has been diagnosed with an infectious disease exhibits changing symptoms.

Brucellosis: Current Status Of The Disease And Future Perspectives

“…Brucella melitensis has been found to be sexually transmitted in sheep and goats. The transmission of brucellosis is facilitated by the intermingling of animal herds that belong to different owners and by the procurement of cattle from sources that are not properly screened for the disease [2]. Moreover, using common male breeding stock also increases the risk of disease transmission among domestic animals.…”

“…Brucellosis is an infectious disease that has been controlled and eradicated in some countries in the world [3]. In sub-Saharan Africa, animal health services have been substantially deteriorated over the last 20 years due to various factors such as reduction in government budgets, especially the funds required to control brucellosis [81] Hence, various programs that require the use of disease prevention measures, information exchange, and coordinated surveillance, are not properly implemented in many sub-Saharan countries [2,18,42,82].…”

“…But for those infected at seven months gestation, abortion may occur after 50 days. Various factors such as age, sex, stage of gestation, infective dose and immune system of the animals may influence the incubation period [2,48]. In very susceptible animals with weak immune systems, abortion occurs during the third trimester and other clinical symptoms include metritis, retained placenta, and reduced milk production [49].…”

“…Brucellosis is an infectious zoonotic disease of domestic animals, as well as humans, globally [1][2][3]. Various domestic animals such as camels, goats, sheep, cows as well as humans are affected by brucellosis.…”

“…Brucellosis is an infectious zoonotic disease of domestic animals, as well as humans, globally [1][2][3].…”