2024
DOI: 10.1073/pnas.2408347121
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A meiotic driver hijacks an epigenetic reader to disrupt mitosis in noncarrier offspring

Yu Hua,
Jianxiu Zhang,
Man-Yun Yang
et al.

Abstract: Killer meiotic drivers (KMDs) are selfish genetic elements that distort Mendelian inheritance by selectively killing meiotic products lacking the KMD element, thereby promoting their own propagation. Although KMDs have been found in diverse eukaryotes, only a limited number of them have been characterized at the molecular level, and their killing mechanisms remain largely unknown. In this study, we identify that a gene previously deemed essential for cell survival in the fission yeast Schizosacchar… Show more

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