A meta-analysis on diagnostic accuracy of serum HLA-G level in breast cancer

Sayad, Soheila; Ahmadi, Seyyed Amir Yasin; Moradi, Mohammad; Negarandeh, Reza; Anbari, Khatereh; Shahsavar, Farhad

doi:10.1080/23808993.2020.1735936

Cited by 9 publications

(8 citation statements)

References 31 publications

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“…However, as other complex disease, the identified loci only explain a minority of the risk of cervical cancer. This gap of the heritability explained by genetic markers genome-wide association studies and the heritability identified in familial studies has been termed as 'missing heritability' (Chen et al, 2016;Leo et al, 2017;Sayad, Ahmadi, Moradi, et al, 2020). Thus, our understanding of the genetic basis of cervical cancer is still limited.…”

Section: Introductionmentioning

confidence: 99%

A Meta-Analysis for Association of XRCC3 rs861539, MTHFR rs1801133, IL-6 rs1800795, IL-12B rs3212227, TNF-α rs1800629, and TLR9 rs352140 Polymorphisms with Susceptibility to Cervical Carcinoma

Parsaeian

Asadian

Karimi-Zarchi

et al. 2021

Asian Pac J Cancer Prev

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Background:In spite of substantial declines in both incidence and mortality rates in the past 50 years, cervical cancer remains one of the leading causes of cancer associated mortality among women globally. We performed this meta-analysis to explore the role of XRCC3 rs861539, MTHFR rs1801133, IL-6 rs1800795, IL-12B rs3212227, TNF-α rs1800629 and TLR9 rs352140 polymorphism with susceptibility to cervical carcinoma. Methods: The search databases include PubMed, SciELO, MedRxiv, Web of Science, Scopus, Cochrane Library, China National Knowledge Infrastructure, and China Biology Medicine disc up to 30 June 2021. The language is limited to English and Chinese. The comparison between the polymorphisms and cervical cancer was assessed using pooled odds ratio (OR) and 95% confidence interval (CI). The data are statistically analyzed by Comprehensive Meta-Analysis (CMA) 2.0 software. Results: A total of 59 studies including seven studies with 1,112 cases and 1,233 controls on XRCC3 rs861539, 14 studies with 2,694 cases and 3349 controls MTHFR rs1801133, four studies with 1,121 cases and 1,109 controls on IL-12B rs3212227, seven studies with 1,452 cases and 2,186 controls on IL-6 rs1800795, 20 studies with 4,781 cases and 4909 controls on TNF-α rs1800629, and seven studies with 1743 cases and 2292 controls on TLR9 rs352140 were included. There was a significant association between XRCC3 RS861539, TNF-α rs1800629, and IL-6 rs1800795 polymorphisms and an increased risk of cervical carcinoma in overall population. However, the MTHFR rs1801133, IL-12B rs3212227 and TLR9 rs352140 polymorphisms were not associated. Conclusion: The pooled analysis showed that XRCC3 RS861539, TNF-α rs1800629, and IL-6 rs1800795 were associated with cervical carcinoma susceptibility, but not MTHFR rs1801133, IL-12B rs3212227 and TLR9 rs352140 polymorphisms.

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Section: Introductionmentioning

confidence: 99%

A Meta-Analysis for Association of XRCC3 rs861539, MTHFR rs1801133, IL-6 rs1800795, IL-12B rs3212227, TNF-α rs1800629, and TLR9 rs352140 Polymorphisms with Susceptibility to Cervical Carcinoma

Parsaeian

Asadian

Karimi-Zarchi

et al. 2021

Asian Pac J Cancer Prev

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“…Between-study heterogeneity may have affected a meta-analysis result when interpreting of the pooled ORs (Edraki et al, 2019;Sayad, Ahmadi, Nekouian, et al, 2020;Sayad, Ahmadi, Moradi, et al, 2020). In the current meta-analysis, significant between study heterogeneity existed for both MTHFR rs1801133 (677C>T) and rs180113 (1298A>C) polymorphisms under most genetic models.…”

Section: Discussionmentioning

confidence: 79%

Associations of MTHFR rs1801133 (677C>T) and rs180113 (1298A>C) Polymorphisms with Susceptibility to Bladder Cancer: A Systematic Review and Meta-Analysis

Farshid

Alijanpour

Barahman

et al. 2022

Asian Pac J Cancer Prev

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“…Thyroid gland metastasis tumors are very rare in clinic. The most common tumors with metastasis to thyroid glands are of breast, lung and skin and kidney primaries, except for lymphoma, leukemia and malignant melanomas (5,6). Diagnosis of metastatic renal cell carcinoma within thyroid gland is challenging using clinical manifestations and radiologic evaluation dut to the non-specific findings.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Metastasis of Renal Clear Cell Carcinoma to the Thyroid Gland, Presenting as a Goiter Nodule, Three Years After Nephrectomy

2020

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Scan to discover online Thyroid gland metastatic tumors are rare in clinical practice. Clear cell RCC is one of common metastatic tumors to thyroid. We here reported a case of incidentally found clear cell renal carcinoma metastasis to the thyroid gland 3 years after nephrectomy, in the thyroidectomy procedure performed for the patient due to the thyroid enlargement caused by multinodular goiter. A 65-year-old Iranian man with a history of multinodular goiter referred to our surgery clinic for thyroidectomy because of compressive effects on the trachea. Patient had a history of nephrectomy due to clear cell RCC 3 years ago. After thyroidectomy, gross and histological examination of thyroid revealed clear cell renal carcinoma metastasis to the thyroid gland in the setting of a multinodular goiter. The diagnosis was confirmed by immunohistochemistry staining. Patients with multinodular goiter are more prone to present with metastasis to thyroid gland if they have a history of malignancy, especially renal cell carcinoma.

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A meta-analysis on diagnostic accuracy of serum HLA-G level in breast cancer

Cited by 9 publications

References 31 publications

A Meta-Analysis for Association of XRCC3 rs861539, MTHFR rs1801133, IL-6 rs1800795, IL-12B rs3212227, TNF-α rs1800629, and TLR9 rs352140 Polymorphisms with Susceptibility to Cervical Carcinoma

A Meta-Analysis for Association of XRCC3 rs861539, MTHFR rs1801133, IL-6 rs1800795, IL-12B rs3212227, TNF-α rs1800629, and TLR9 rs352140 Polymorphisms with Susceptibility to Cervical Carcinoma

Associations of MTHFR rs1801133 (677C>T) and rs180113 (1298A>C) Polymorphisms with Susceptibility to Bladder Cancer: A Systematic Review and Meta-Analysis

A Rare Case of Metastasis of Renal Clear Cell Carcinoma to the Thyroid Gland, Presenting as a Goiter Nodule, Three Years After Nephrectomy

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