Abstract:Thiols were effectively oxidized into disulfides by reacting with hydrogen peroxide in the presence of a catalytic amount of iodide ion or iodine.The controlled oxidative coupling of thiols to disulfides is important in organic synthesis, and a wide range of methods have been developed for this transformation. 1 Thiols are among the functional groups which can be easily over oxidized, therefore, extensive studies have been carried out for their controlled oxidation with molecular oxygen, 2 peroxide, 3 metal ox… Show more
“…The oxidation of cysteine catalyzed by I -/H 2 O 2 is attributed to the sequence of reactions outlined in Figure 1 [35]. In the primary step, α-glucosidase and GOD catalyze the aerobic production of H 2 O 2 (eqs.…”
Section: -/H 2 O 2 Catalyzed Oxidation Of Cysteinementioning
confidence: 99%
“…A color change from wine red to violet can be observed. However, in the presence of iodide ions and H 2 O 2 , cysteine is oxidized to cystine and the oxidation product cystine cannot lead to aggregation of AuNPs [35]. In this work, maltose is used as the nature substrate of α-glucosidase to conduct our proposed sensing approach.…”
“…The oxidation of cysteine catalyzed by I -/H 2 O 2 is attributed to the sequence of reactions outlined in Figure 1 [35]. In the primary step, α-glucosidase and GOD catalyze the aerobic production of H 2 O 2 (eqs.…”
Section: -/H 2 O 2 Catalyzed Oxidation Of Cysteinementioning
confidence: 99%
“…A color change from wine red to violet can be observed. However, in the presence of iodide ions and H 2 O 2 , cysteine is oxidized to cystine and the oxidation product cystine cannot lead to aggregation of AuNPs [35]. In this work, maltose is used as the nature substrate of α-glucosidase to conduct our proposed sensing approach.…”
“…The disulfide bond formation method reported by M. Kirihara et al was adopted [53]. First, 100 mg of SHGO was dispersed in 30 ml ethyl acetate (CH 3 CO 2 C 2 H 5 , EtOAc).…”
Section: Disulfide-linking Between Shgo and Linker Moleculesmentioning
“…45 Hydrogen peroxide and peroxyacids are commonly used reagents to oxidize thiols to disulfides, although it is easy to observe byproducts at various oxidation states. 46 A number of selective protocols of oxidation such as water solution of hydrogen peroxide in alcohols as media, 47 48 and catalytic NaI with a stoichiometric amount of 30% hydrogen peroxide 49 have been developed. The hydrogen peroxide urea adduct, UHP, is activated toward the oxidative coupling of thiols by maleic anhydride, whereas aromatic cyclic seleninate esters and spirodioxyselenuranes mediate the oxidation of thiols to disulfides in the presence of H 2 O 2 .…”
Section: By Metal Complexes/dioxygen Source Inorganic Salts and Permentioning
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