A Mini-Review on Newcastle Disease Virus in Egypt, With Particular References to Common Vaccines and Their Development

Ali, Adel A.; Abdallah, Fatma; Farag, Gamelat K.; Sameh, karim

doi:10.21608/zvjz.2022.104225.1161

Cited by 5 publications

(5 citation statements)

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“…Low-virulent lentogenic NDV strains are those that induce subclinical infection and moderate respiratory or gastrointestinal illness. However, the disease produced by mesogenic strains are of intermediate virulence and cause respiratory infection with moderate mortality, while velogenic NDV strains are highly virulent and can result in mortality rates of up to 100% Alexander DJ [66], Ebrahimi MM, et al [78], Pantin-Jackwood MJ, et al [153], Ali A, et al [154], which prompts trade restrictions and embargoes in the nations where the illness is present [65,155]. Viscotropic and neurotropic velogenic strains are additional categories for velogenic strains.…”

Section: Pathogenicity Of Newcastle Diseasementioning

confidence: 99%

Possible Outbreak of Newcastle Virus Infection in the Face of Increasing Trend of Backyard Poultry Farm Management Interface in Nigeria: A Public Health and Food Security Threat

Obioma,

SC,

2024

JQHE

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Introduction: Newcastle disease is a highly contagious illness and one of the "notifiable illnesses" on the World Health Organization list for Animal Health (OIE) Outcome. There are constantly new cases being reported as new NDV isolates from around the world. Newcastle disease poses a significant global economic threat to the poultry sector, causing highly contagious and transmissible diseases in birds with huge food security threat among the weak and vulnerable developing and underdeveloped countries Aim: The aim of this article borders on bringing to light the risk of possible Newcastle disease outbreak in Nigeria due to increasing poor management of poultry farms and poultry waste product. Furthermore, it will also underscore and outline various ways which can be adopted to prevent this poultry disease which is of great public health, economic and food security protection importance. Method/Methodology: This is a systematic review of published research articles focusing on Newcastle disease, epidemiology, pathogenicity, transmission and factors that can play important roles in the possible outbreak of the disease in poultries. Studies reviewed comprise of cross-sectional, prospective, longitudinal and observational studies. The study approach follows the systematic review of peer-reviewed published articles as well as online publications and articles derived from various databases with search keywords relevant to the topic of discourse. Findings and Results: The findings in this study highlight the endemicity of Newcastle virus disease in various part of the country, and how the severity of the disease is influenced by host characteristics, viral properties, and environmental factors. The study pointed out critical evidence-based possible reasons that could promote a new round of Newcastle disease epidemic outbreak as a result of poor poultry management practices such as high bird densities, poor poultry infrastructure, lack of quarantine of sick birds, mixed species rearing, free range system of poultry, poor waste disposal, lack of expertise, and insufficient biosecurity outcomes. However, the lack of education and awareness among farmers exacerbates the problem, hindering preventive measures. The complexity is increased by difficulties with vaccination, unrestrained bird movement through trading with neighboring countries and interstate, and a lack of diagnostic facilities. The consequences of an outbreak extends beyond financial losses to potential disruptions in the poultry supply chain, food security risks, and public health concerns. Conclusion and Recommendation: The growing difficulties in poultry management methods increases the serious public health concern posed by a possible Newcastle Virus epidemic outbreak in Nigeria. A paradigm shift in poultry farming practices is necessary to address this problem. A comprehensive strategy that incorporates infrastructural development, regulatory frameworks, and education in order to strengthen the poultry industry is needed, so as to address and prevent the looming public health and food security crises that may break out from the above scenario

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Section: Pathogenicity Of Newcastle Diseasementioning

confidence: 99%

Possible Outbreak of Newcastle Virus Infection in the Face of Increasing Trend of Backyard Poultry Farm Management Interface in Nigeria: A Public Health and Food Security Threat

Obioma,

SC,

2024

JQHE

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“…Lentogenic viruses cause few clinical symptoms but when they do, they are mainly respiratory in origin. In general, avirulent viruses do not produce any clinical symptoms (Ali et al, 2022).…”

Section: Clinical Symptomsmentioning

confidence: 99%

Isolation of newcastle disease virus from commercial broilers in district Abbottabad, Khyber Pakhtunkhwa, Pakistan

Saba,

Yousaf,

Dad

et al. 2023

Zoo Bot.

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The present study was carried out to isolate Newcastle disease virus in commercial broilers in district Abbottabad, KPK, Pakistan from January to June 2023. A total 60 broilers were swab sampled (cloacal and tracheal swabs) i.e. 120 swab samples were collected. The reverse transcription polymerase chain reaction procedure was done for isolation of Newcastle disease virus in National Reference Laboratory for Poultry Disease, Islamabad. Results revealed that out of total samples, only 5 tested positive for the Newcastle disease virus, indicating a prevalence percentage of 8.33%. Among the different areas surveyed, Qalandar Abad exhibited the highest occurrence of the Newcastle disease virus, with a prevalence rate of 20%. These findings highlight the geographical disparity in Newcastle disease virus prevalence and imply potential variations in risk factors or biosecurity measures among different regions within the district.

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“…Newcastle Disease Virus termasuk dalam strain virus Avian paramyxovirus type-1, famili Paramyxoviridae, genus Avulavirus (Worku and Teshome, 2020). Virus ini mengkode 6 protein utama yaitu Protein Fusion (F), Hemaglutinin-neuraminidase (HN), dan Matrix (M) semuanya terkait dengan amplop virus, sedangkan tiga protein yang lain terkait dengan RNA genomik: nukleokapsid (NP), fosfoprotein (P), dan RNA polimerase (L) (Ali et al, 2022). Sepanjang studi molekuler, protein yang menjadi peran kunci dalam masuknya virus ke dalam yaitu protein F dan protein HN.…”

Section: Pendahuluanunclassified

“…Virus ND memiliki protein hemaglutinin-neuraminidase (HN) yang yang berada pada amplop virus (Ali et al, 2022). Adanya protein hemaglutinin (H) menyebabkan terjadinya hemaglutinasi karena adanya ikatan antara protein hemaglutinin dengan reseptor permukaan eritrosit (Fitrawati et al, 2015).…”

Section: Hemaglutinasiunclassified

AKTIVITAS ANTIVIRUS EKSTRAK ETANOL BAWANG PUTIH (Allium sativum L.) TERHADAP MODEL NEWCASTLE DISEASE

Azizah,

Saifudin

2023

ujp

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Bahan alam, baik sebagai senyawa murni atau ekstrak dari tanaman memberikan peluang sebagai agen antivirus. Bawang putih merupakan tanaman herba yang dikonsumsi di seluruh dunia yang memiliki kandungan senyawa aktif di dalamnya yang telah diteliti memiliki aktivitas farmakologi seperti antibakteri, antivirus, antijamur, antiprotozoal, antioksidan, antiinflamasi, antikanker. Senyawa aktif dalam bawang putih yang dilaporkan berperan besar sebagai antivirus yaitu ajoene, alisin, alil metil thiosulfinat, dan metil alil thiosulfinat. Penelitian bertujuan untuk mengetahui aktivitas antivirus ekstrak etanol bawang putih terhadap model Newcastle Disease. Uji antivirus dilakukan dengan media telur ayam berembrio (TAB) usia 9-12 hari yang diinokulasi virus aktif ND La Sota dan ekstrak etanol bawang putih dengan variasi konsentrasi 1 µg/mL, 10 µg/mL, dan 100 µg/mL dengan metode in ovo. Validitas uji didasarkan atas hidupnya virus yang tampak adanya kejernihan pada larutan kultur pasca perlakuan. Aktivitas antivirus dievaluasi menggunakan uji hemaglutinasi dengan bahan uji cairan alantois yang sudah dipanen untuk mendapatkan titer virus yang digunakan untuk menghitung persen penghambatan virus. Hasil menunjukkan bahwa tidak adanya aktivitas antivirus pada ekstrak dengan variasi konsentrasi 1 µg/mL, 10 µg/mL, dan 100 µg/mL dengan persen penghambatan virus ketiga seri konsentrasi 0%.

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A Mini-Review on Newcastle Disease Virus in Egypt, With Particular References to Common Vaccines and Their Development

Cited by 5 publications

References 0 publications

Possible Outbreak of Newcastle Virus Infection in the Face of Increasing Trend of Backyard Poultry Farm Management Interface in Nigeria: A Public Health and Food Security Threat

Possible Outbreak of Newcastle Virus Infection in the Face of Increasing Trend of Backyard Poultry Farm Management Interface in Nigeria: A Public Health and Food Security Threat

Isolation of newcastle disease virus from commercial broilers in district Abbottabad, Khyber Pakhtunkhwa, Pakistan

AKTIVITAS ANTIVIRUS EKSTRAK ETANOL BAWANG PUTIH (Allium sativum L.) TERHADAP MODEL NEWCASTLE DISEASE

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