A mitochondrion targetable dimethylphosphorothionate-based far-red and colorimetric fluorescent probe with large Stokes shift for monitoring peroxynitrite in living cells

Abstract

Peroxynitrite (ONOO−) is a biological oxidant that is related to many physiological and pathological processes. An overdose of ONOO− is the cause of various serious diseases. Some evidences demonstrated that...

A novel “turn on” fluorescence probe based on a caffeic acid skeleton for detecting Al3+ and bioimaging application

“…The optimized structures of probe HAM and complex HAM-Al 3+ were conducted using the density functional theory (DFT) Analytical Methods Paper calculation with Gaussian 09 programs, 35,36 as illustrated in Fig. 5.…”

A resorufin-based fluorescent probe for hydrazine detection and its application in environmental analysis and bioimaging

“…29,30 However, all these detection methods usually have some shortcomings and rely on expensive instruments. [31][32][33][34][35][36][37][38] In contrast, a uorescent probe has become an ideal detection method owing to its advantages of convenient operation, high specicity, good sensitivity and real-time monitoring. [39][40][41][42][43] Although some uorescent probes with great advantages of sensitivity and selectivity have been reported, more efficient, easily synthesized and low-cost probes still need to be developed to achieve highly efficient detection of N 2 H 4 in complex environments and biological samples.…”

A perylenemonoimide-based fluorescent probe: ultrasensitive and selective tracing of endogenous peroxynitrite in living cells

“…Peroxynitrite (ONOO − ) has been well-known as a strong oxidant in physiological and pathological processes. [1][2][3] It is formed by the reaction between the superoxide radical anion (O 2…”

“…Peroxynitrite (ONOO − ) has been well-known as a strong oxidant in physiological and pathological processes. 1–3 It is formed by the reaction between the superoxide radical anion (O 2 ˙ − ) and nitric oxide (NO) under physiological conditions. 4,5 The normal level of endogenously generated ONOO − plays a crucial role in antimicrobial activity and cell signal transduction pathways.…”