“…The PAI module was about 2-inch diameter and made up of a modular photoacoustic hat to cover the entire neonatal brain ( Fig. 8 a) [ 127 ]. Tavakolian et al developed a neonatal brain imaging device built in a phantom skull model and customized PAI system ( Fig.…”
Section: Photoacoustic Imaging For Strokementioning
confidence: 99%
“… Fig. 8 Schematic of PAI caps for human brain: (a) Spherical cap transducer arrays around the human head and the picture of a single piezoelectric micromachined ultrasound transducer array with light fiber bundles (adapted from [ 127 ]), (b) 3D models of the skull phantom and structure of PAI system (adapted from [ 128 ]). …”
Section: Photoacoustic Imaging For Strokementioning
Highlights
Summarizes photoacoustic imaging for monitoring of stroke diseases.
Focuses on the potential photoacoustic systems for human monitoring.
Reports the challenges of stroke monitoring in the human brain.
“…The PAI module was about 2-inch diameter and made up of a modular photoacoustic hat to cover the entire neonatal brain ( Fig. 8 a) [ 127 ]. Tavakolian et al developed a neonatal brain imaging device built in a phantom skull model and customized PAI system ( Fig.…”
Section: Photoacoustic Imaging For Strokementioning
confidence: 99%
“… Fig. 8 Schematic of PAI caps for human brain: (a) Spherical cap transducer arrays around the human head and the picture of a single piezoelectric micromachined ultrasound transducer array with light fiber bundles (adapted from [ 127 ]), (b) 3D models of the skull phantom and structure of PAI system (adapted from [ 128 ]). …”
Section: Photoacoustic Imaging For Strokementioning
Highlights
Summarizes photoacoustic imaging for monitoring of stroke diseases.
Focuses on the potential photoacoustic systems for human monitoring.
Reports the challenges of stroke monitoring in the human brain.
“…Their practical realization typically suffers from the complex assembly, unviability of full-hat rotation around the human head, US coupling and the necessity of hundreds of US data acquisition channels required to cover the whole brain. Last year, a modular PAI hat was developed for neonatal brain imaging, consisting of multiple PAI disc modules, measuring 2 inches in diameter [53]. Conforming to the shape of the head, these modules were assembled onto a hat to cover the entire neonatal brain.…”
Section: Achievements Of Pai Techniques In the Past Five Yearsmentioning
For combining optical and ultrasonic imaging methodologies, photoacoustic imaging (PAI) is the most important and successful hybrid technique, which has greatly contributed to biomedical research and applications. Its theoretical background is based on the photoacoustic effect, whereby a modulated or pulsed light is emitted into tissue, which selectively absorbs the optical energy of the light at optical wavelengths. This energy produces a fast thermal expansion in the illuminated tissue, generating pressure waves (or photoacoustic waves) that can be detected by ultrasonic transducers. Research has shown that optical absorption spectroscopy offers high optical sensitivity and contrast for ingredient determination, for example, while ultrasound has demonstrated good spatial resolution in biomedical imaging. Photoacoustic imaging combines these advantages, i.e., high contrast through optical absorption and high spatial resolution due to the low scattering of ultrasound in tissue. In this review, we focus on advances made in PAI in the last five years and present categories and key devices used in PAI techniques. In particular, we highlight the continuously increasing imaging depth achieved by PAI, particularly when using exogenous reagents. Finally, we discuss the potential of combining PAI with other imaging techniques.
“…The electromagnetic properties of light in conjunction with the penetrability of sound have made it possible to penetrate deeper and obtain information that is functional to the target thus probed. Pulsed LEDs and MUTs [24][25][26][27][28][29][30][31][32][33][34][35][36][37] have revolutionized the field further, thereby creating wearable photoacoustic devices. In this work, we have fabricated piezoelectric micromachined ultrasound transducers (PMUTs) using functional thin-film piezoelectric material and the nanofabrication tools and have demonstrated their use as a photoacoustic receiver.…”
We report on the development of a novel piezo-MEMS based optofluidic platform to detect the concentration of various species dissolved in a fluid. This platform employs piezoelectric micromachined ultrasound transducers (PMUTs) to work as a photoacoustic receiver, receiving ultrasound from fluid targets present in microfluidic channels while illuminated with a nanosecond pulsed laser. We fabricate both the PMUTs and the microfluidic channels and subsequently use them for the experiment. We also show the capability of PMUTs as a general photoacoustic receiver and demonstrate its signal-to-noise characteristics (~31) and its wide fractional bandwidth (~73%).
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