A multi-channel electrochemical biosensor based on polyadenine tetrahedra for the detection of multiple drug resistance genes

Song, Yanan; Feng, Jun; Wang, Xueming; Wen, Yanli; Xu, Li; Huo, Yinbo; Wang, Lele; Tao, Qing; Yang, Zhenzhou; Liu, Gang; Chen, Min; Li, Lanying; Yan, Juan

doi:10.1039/d4an00488d

Analyst

2024

DOI: 10.1039/d4an00488d

|View full text |Cite

A multi-channel electrochemical biosensor based on polyadenine tetrahedra for the detection of multiple drug resistance genes

Yanan Song,

Jun Feng,

Xueming Wang

et al.

Abstract: Antimicrobial resistance poses a serious threat to human health due to the high morbidity and mortality caused by drug-resistant gene infections. Therefore, the development of rapid, sensitive and selective identification...

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Development of a Novel Colorimetric pH Biosensor Based on A-Motif Structures for Rapid Food Freshness Monitoring and Spoilage Detection

Wang,

Zhang

et al. 2024

Biosensors

View full text Add to dashboard Cite

Accurate methods for assessing food freshness through colorimetric pH response play a critical role in determining food spoilage and ensuring food quality standards. This study introduces a novel unlabeled DNA sequence, poly-dA20, designed to exploit the colorimetric properties of both the single strand and the fold-back A-motif structure in conjunction with gold nanoparticles (AuNPs) under varying pH conditions. When exposed to storage temperatures of 4 °C and 25 °C, the color variations in the AuNP solution, influenced by pH level changes in mutton and sea bass samples’ different storage periods, are easily discernible to the naked eye within a minute. The ratio of UV absorption values at 527 nm and 700 nm (A527/A700) demonstrates a strong linear correlation with both the storage duration and pH of the food samples. Furthermore, a comprehensive analysis combining the total volatile basic nitrogen (TVB-N) value with the A527/A700 ratio is employed for precise assessment of food freshness. The innovative pH-responsive sensing strategy not only provides a new approach for on-site food freshness and spoilage detection systems but also serves as a valuable tool for pH-related biological detection in clinical diagnostic applications.

show abstract

Development of a Novel Colorimetric pH Biosensor Based on A-Motif Structures for Rapid Food Freshness Monitoring and Spoilage Detection

Wang,

Zhang

et al. 2024

Biosensors

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

A multi-channel electrochemical biosensor based on polyadenine tetrahedra for the detection of multiple drug resistance genes

Abstract: Antimicrobial resistance poses a serious threat to human health due to the high morbidity and mortality caused by drug-resistant gene infections. Therefore, the development of rapid, sensitive and selective identification...

Cited by 1 publication

References 36 publications

Development of a Novel Colorimetric pH Biosensor Based on A-Motif Structures for Rapid Food Freshness Monitoring and Spoilage Detection

Development of a Novel Colorimetric pH Biosensor Based on A-Motif Structures for Rapid Food Freshness Monitoring and Spoilage Detection

Contact Info

Product

Resources

About