A multi-functional 3D-printable gel-in-gel system for the delivery of probiotics to the intestine

Fan, Di; Diller, Silvia; Mansi, Salma; Wang, Chen; Mela, Petra; Özkale, Berna; Lieleg, Oliver

doi:10.1016/j.foodhyd.2024.110267

Food Hydrocolloids

2024

DOI: 10.1016/j.foodhyd.2024.110267

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A multi-functional 3D-printable gel-in-gel system for the delivery of probiotics to the intestine

Di Fan,

Silvia Diller,

Salma Mansi

et al.

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Cited by 3 publications

References 73 publications

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3D extrusion bioprinting of microbial inks for biomedical applications

Burns,

Rajesh,

Manjula-Basavanna

et al. 2025

Advanced Drug Delivery Reviews

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3D extrusion bioprinting of microbial inks for biomedical applications

Burns,

Rajesh,

Manjula-Basavanna

et al. 2025

Advanced Drug Delivery Reviews

View full text Add to dashboard Cite

Advancements of Biomacromolecular Hydrogel Applications in Food Nutrition and Health

Ye,

Sun,

Xiang

et al. 2024

J. Agric. Food Chem.

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Hydrogels exhibit remarkable degradability, biocompatibility and functionality, which position them as highly promising materials for applications within the food and pharmaceutical industries. Although many relevant studies on hydrogels have been reported in the chemical industry, materials, and other fields, there have been few reviews on their potential applications in food nutrition and human health. This study aims to address this gap by reviewing the functional properties of hydrogels and assessing their value in terms of food nutrition and human health. The use of hydrogels in preserving bioactive ingredients, food packaging and food distribution is delved into specifically in this review. Hydrogels can serve as cutting-edge materials for food packaging and delivery, ensuring the preservation of nutritional activity within food products, facilitating targeted delivery of bioactive compounds and regulating the digestion and absorption processes in the human body, thereby promoting human health. Moreover, hydrogels find applications in in vitro cell and tissue culture, human tissue repair, as well as chronic disease prevention and treatment. These broad applications have attracted great attention in the fields of human food nutrition and health. Ultimately, this paper serves as a valuable reference for further utilization and exploration of hydrogels in these respective fields.

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Next-Generation Probiotics and Chronic Diseases: A Review of Current Research and Future Directions

Tiwari,

Ika Krisnawati,

Susilowati

et al. 2024

J. Agric. Food Chem.

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The burgeoning field of microbiome research has profoundly reshaped our comprehension of human health, particularly highlighting the potential of probiotics and fecal microbiota transplantation (FMT) as therapeutic interventions. While the benefits of traditional probiotics are well-recognized, the efficacy and mechanisms remain ambiguous, and FMT's long-term effects are still being investigated. Recent advancements in high-throughput sequencing have identified gut microbes with significant health benefits, paving the way for next-generation probiotics (NGPs). These NGPs, engineered through synthetic biology and bioinformatics, are designed to address specific disease states with enhanced stability and viability. This review synthesizes current research on NGP stability, challenges in delivery, and their applications in preventing and treating chronic diseases such as diabetes, obesity, and cardiovascular diseases. We explore the physiological characteristics, safety profiles, and mechanisms of action of various NGP strains while also addressing the challenges and opportunities presented by their integration into clinical practice. The potential of NGPs to revolutionize microbiome-based therapies and improve clinical outcomes is immense, underscoring the need for further research to optimize their efficacy and ensure their safety.

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A multi-functional 3D-printable gel-in-gel system for the delivery of probiotics to the intestine

Cited by 3 publications

References 73 publications

3D extrusion bioprinting of microbial inks for biomedical applications

3D extrusion bioprinting of microbial inks for biomedical applications

Advancements of Biomacromolecular Hydrogel Applications in Food Nutrition and Health

Next-Generation Probiotics and Chronic Diseases: A Review of Current Research and Future Directions

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