A multi-responsive self-healing hydrogel for controlled release of curcumin

Pan, Ruihao; Liu, Guoqiang; Zeng, Yuan; He, Xianzhe; Ma, Zeyu; Wei, Yen; Chen, Shengli; Yang, Lei; Tao, Lei

doi:10.1039/d1py00176k

Cited by 32 publications

(21 citation statements)

References 49 publications

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“…Dynamic borate hydrogel can also improve the bioavailability of poorly water-soluble drugs (such as curcumin) [ 26 ]. Ruihao Pan et al developed a multi-responsive self-healing hydrogel for the controlled release of curcumin by using a dynamic borate ester bond.…”

Section: Mechanism Of Self-healing Hydrogelsmentioning

confidence: 99%

Mechanism of Self-Healing Hydrogels and Application in Tissue Engineering

Liang

Yuan

et al. 2022

Polymers

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Self-healing hydrogels and traditional hydrogels both have three-dimensional polymeric networks that are capable of absorbing and retaining a large amount of water. Self-healing hydrogels can heal and restore damage automatically, and they can avoid premature failure of hydrogels caused by mechanical damage after implantation. The formation mechanism of self-healing hydrogels and the factors that hydrogels can load are various. Researchers can design hydrogels to meet the needs of different tissues through the diversity of hydrogels Therefore, it is necessary to summarize different self-healing mechanisms and different factors to achieve different functions. Here, we briefly reviewed the hydrogels designed by researchers in recent years according to the self-healing mechanism of water coagulation. Then, the factors for different functions of self-healing hydrogels in different tissues were statistically analyzed. We hope our work can provide effective support for researchers in the design process of self-healing hydrogel.

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Section: Mechanism Of Self-healing Hydrogelsmentioning

confidence: 99%

Mechanism of Self-Healing Hydrogels and Application in Tissue Engineering

Liang

Yuan

et al. 2022

Polymers

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“…Due to the precedence of the use of pH as a stimulus to control the release of drugs from gels, 48 we explored the controlled release of curcumin from the curcumin entrapped gel using the former as a trigger. The curcumin release experiments were carried out from the curcumin entrapped gel at different pH values using phosphate buffer solution (PBS) at 25 1C.…”

Section: Curcumin Release With Ph As Stimulusmentioning

confidence: 99%

Structure–gelation property relationships of phenolic glycosides of pentose sugars: pH dependent controlled release of curcumin

2022

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“…Very recently, introducing dynamic covalent bonds into networks has offered a promising strategy to develop inherently degradable resin/carbon fiber composites. Several typical degradable thermosets based on acetals, [15][16][17] borate esters, 18,19 imines, [20][21][22][23] and disulfides 24,25 have been explored. These typical systems are all focused on exploring the degradation of thermosetting resin matrices and efficient recycling of woven CFs by controlling the reversible behaviour of dynamic covalent bonds.…”

Section: Introductionmentioning

confidence: 99%