“…It is often easier to heal minor wounds, while severe traumas require medical dressing to assist in their recovery. Currently, various synthetic and natural materials, such as chitosan, sodium alginate (SA), collagen, and so on, are developed to manufacture wound dressings. − Among these materials, SA as a renewable marine biomaterial could be cross-linked with multivalent metal cations (Ca 2+ , Cu 2+ , and Fe 3+ ) to form a stable matrix . Moreover, owing to its good biocompatibility, biodegradability, and hemostatic ability, SA has great application potential in inventing wound dressing platforms in clinical use. − However, SA shows no antibacterial property, and most of the patients lost their protection of skin at the wound part, which can easily cause bacterial infections, leading to serious consequences.…”